Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection

Katharine E. Yoder; Michele L. Shaffer; Susan J. La Tournous; Ian M. Paul

doi:10.1177/0009922806291014

Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection

Katharine E. Yoder, Michele L. Shaffer, Susan J. La Tournous, Ian M. Paul

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

This study sought to investigate the efficacy of dextromethorphan (DM), diphenhydramine (DPH), and placebo (PL) for symptoms attributed to upper respiratory infections as determined by children, and to evaluate the concordance of perception of nocturnal symptoms between children and parents. A total of 37 children age 6 to 18 years of age were randomized in a double-masked fashion to receive a single bedtime dose of DM, DPH, or PL. Children found no significant difference in the effect of DM, DPH, or PL for any study outcome, and responses by parents and children were significantly correlated.

Original language	English (US)
Pages (from-to)	633-640
Number of pages	8
Journal	Clinical Pediatrics
Volume	45
Issue number	7
DOIs	https://doi.org/10.1177/0009922806291014
State	Published - Sep 2006

All Science Journal Classification (ASJC) codes

Pediatrics, Perinatology, and Child Health

Access to Document

10.1177/0009922806291014

Cite this

@article{1e68f3f8e185469b9deee03adadac4d9,

title = "Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection",

abstract = "This study sought to investigate the efficacy of dextromethorphan (DM), diphenhydramine (DPH), and placebo (PL) for symptoms attributed to upper respiratory infections as determined by children, and to evaluate the concordance of perception of nocturnal symptoms between children and parents. A total of 37 children age 6 to 18 years of age were randomized in a double-masked fashion to receive a single bedtime dose of DM, DPH, or PL. Children found no significant difference in the effect of DM, DPH, or PL for any study outcome, and responses by parents and children were significantly correlated.",

author = "Yoder, {Katharine E.} and Shaffer, {Michele L.} and {La Tournous}, {Susan J.} and Paul, {Ian M.}",

year = "2006",

month = sep,

doi = "10.1177/0009922806291014",

language = "English (US)",

volume = "45",

pages = "633--640",

journal = "Clinical Pediatrics",

issn = "0009-9228",

publisher = "SAGE Publications Inc.",

number = "7",

}

TY - JOUR

T1 - Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection

AU - Yoder, Katharine E.

AU - Shaffer, Michele L.

AU - La Tournous, Susan J.

AU - Paul, Ian M.

PY - 2006/9

Y1 - 2006/9

N2 - This study sought to investigate the efficacy of dextromethorphan (DM), diphenhydramine (DPH), and placebo (PL) for symptoms attributed to upper respiratory infections as determined by children, and to evaluate the concordance of perception of nocturnal symptoms between children and parents. A total of 37 children age 6 to 18 years of age were randomized in a double-masked fashion to receive a single bedtime dose of DM, DPH, or PL. Children found no significant difference in the effect of DM, DPH, or PL for any study outcome, and responses by parents and children were significantly correlated.

AB - This study sought to investigate the efficacy of dextromethorphan (DM), diphenhydramine (DPH), and placebo (PL) for symptoms attributed to upper respiratory infections as determined by children, and to evaluate the concordance of perception of nocturnal symptoms between children and parents. A total of 37 children age 6 to 18 years of age were randomized in a double-masked fashion to receive a single bedtime dose of DM, DPH, or PL. Children found no significant difference in the effect of DM, DPH, or PL for any study outcome, and responses by parents and children were significantly correlated.

UR - http://www.scopus.com/inward/record.url?scp=33747109096&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33747109096&partnerID=8YFLogxK

U2 - 10.1177/0009922806291014

DO - 10.1177/0009922806291014

M3 - Article

C2 - 16928841

AN - SCOPUS:33747109096

SN - 0009-9228

VL - 45

SP - 633

EP - 640

JO - Clinical Pediatrics

JF - Clinical Pediatrics

IS - 7

ER -

Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this