Cholesterol Screening in Children: Is a Universal Approach Working?

Tracie K. Lin, Thomas C. Dispenza

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Purpose of Review: Ample evidence supports that an individual’s lifetime risk of atherosclerotic cardiovascular disease correlates to long-term, cumulative exposure to circulating cholesterol levels, beginning in childhood. Selective screening strategies based on family history fail to identify many children with hypercholesterolemia. Universal cholesterol screening in childhood is a worthwhile goal. However, cholesterol screening rates through childhood remain low. Recent Findings: Mounting evidence clarifies the barriers to cholesterol screening in children. Specific strategies to foster universal screening in childhood have been proposed. Summary: We present an overview of the present state of childhood cholesterol screening, summarizing historical and contemporary guidelines and collating evidence of low adherence to current guidelines. We contend that novel approaches to universal cholesterol screening in childhood are warranted, and we present potential opportunities for improvement. We call for new and universal pediatric cholesterol screening guidelines.

Original languageEnglish (US)
Pages (from-to)579-590
Number of pages12
JournalCurrent atherosclerosis reports
Issue number9
StatePublished - Sep 2023

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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