TY - JOUR
T1 - Chondronecrosis of the hip
T2 - The protective role of the ossific nucleus in an animal model
AU - Segal, Lee S.
AU - Berlin, Joshua M.
AU - Schneider, David J.
AU - Moulton, Mark J.R.
AU - Frauenhoffer, Elizabeth E.
PY - 2000
Y1 - 2000
N2 - The presence of the ossific nucleus and its role in reducing the risk of ischemic necrosis in developmental dysplasia of the hip remains a matter of controversy. Ischemic necrosis of the preosseous capital femoral epiphysis, defined as chondronecrosis, was evaluated in a rabbit model. Histologic evidence of chondronecrosis after casting in maximum abduction was greater in 1-day-old New Zealand White rabbits before the radiographic appearance of the ossific nucleus, compared with 16-day-old New Zealand White rabbits with an ossific nucleus already present. This preliminary study supports the hypothesis that the ossific nucleus may decrease the risk of intracapsular compressive ischemic injury to the developing capital femoral epiphysis in a rabbit model.
AB - The presence of the ossific nucleus and its role in reducing the risk of ischemic necrosis in developmental dysplasia of the hip remains a matter of controversy. Ischemic necrosis of the preosseous capital femoral epiphysis, defined as chondronecrosis, was evaluated in a rabbit model. Histologic evidence of chondronecrosis after casting in maximum abduction was greater in 1-day-old New Zealand White rabbits before the radiographic appearance of the ossific nucleus, compared with 16-day-old New Zealand White rabbits with an ossific nucleus already present. This preliminary study supports the hypothesis that the ossific nucleus may decrease the risk of intracapsular compressive ischemic injury to the developing capital femoral epiphysis in a rabbit model.
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U2 - 10.1097/00003086-200008000-00034
DO - 10.1097/00003086-200008000-00034
M3 - Review article
C2 - 10943210
AN - SCOPUS:0033863664
SN - 0009-921X
SP - 265
EP - 271
JO - Clinical orthopaedics and related research
JF - Clinical orthopaedics and related research
IS - 377
ER -