Clinical correlation with serum-soluble interleukin-2 receptor levels in guillain-barré syndrome

S. Bansil; F. A. Mithen; S. D. Cook; A. Sheffet; C. Rohowsky-Kochan

doi:10.1212/wnl.41.8.1302

Clinical correlation with serum-soluble interleukin-2 receptor levels in guillain-barré syndrome

S. Bansil
, F. A. Mithen
, S. D. Cook
, A. Sheffet
, C. Rohowsky-Kochan

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

In patients with Guillain-Barré syndrome (GBS) soluble interleukin-2 receptor (sIL-2R) levels were elevated compared with those of patients with other neurologic diseases (OND), and of healthy controls. Smaller increases in sIL-2R levels occurred in OND patients compared to healthy subjects. Monitoring of GBS patients clearly demonstrated that decreases in sIL-2R levels correlated with clinical recovery. Thus, T-cell activation may be relevant in the pathogenesis of GBS.

Original language	English (US)
Pages (from-to)	1302-1305
Number of pages	4
Journal	Neurology
Volume	41
Issue number	8
DOIs	https://doi.org/10.1212/wnl.41.8.1302
State	Published - Aug 1991

All Science Journal Classification (ASJC) codes

Clinical Neurology

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10.1212/wnl.41.8.1302

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abstract = "In patients with Guillain-Barr{\'e} syndrome (GBS) soluble interleukin-2 receptor (sIL-2R) levels were elevated compared with those of patients with other neurologic diseases (OND), and of healthy controls. Smaller increases in sIL-2R levels occurred in OND patients compared to healthy subjects. Monitoring of GBS patients clearly demonstrated that decreases in sIL-2R levels correlated with clinical recovery. Thus, T-cell activation may be relevant in the pathogenesis of GBS.",

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AU - Sheffet, A.

AU - Rohowsky-Kochan, C.

PY - 1991/8

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N2 - In patients with Guillain-Barré syndrome (GBS) soluble interleukin-2 receptor (sIL-2R) levels were elevated compared with those of patients with other neurologic diseases (OND), and of healthy controls. Smaller increases in sIL-2R levels occurred in OND patients compared to healthy subjects. Monitoring of GBS patients clearly demonstrated that decreases in sIL-2R levels correlated with clinical recovery. Thus, T-cell activation may be relevant in the pathogenesis of GBS.

AB - In patients with Guillain-Barré syndrome (GBS) soluble interleukin-2 receptor (sIL-2R) levels were elevated compared with those of patients with other neurologic diseases (OND), and of healthy controls. Smaller increases in sIL-2R levels occurred in OND patients compared to healthy subjects. Monitoring of GBS patients clearly demonstrated that decreases in sIL-2R levels correlated with clinical recovery. Thus, T-cell activation may be relevant in the pathogenesis of GBS.

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Clinical correlation with serum-soluble interleukin-2 receptor levels in guillain-barré syndrome

Abstract

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