Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups

Marina B. Martinez; Thomas S. Whittan; Elizabeth A. McGraw; Josias Rodrigues; Luiz R. Trabulsi

doi:10.1016/S0378-1097(99)00031-2

Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups

Marina B. Martinez, Thomas S. Whittan, Elizabeth A. McGraw, Josias Rodrigues, Luiz R. Trabulsi

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

The genetic relatedness among 96 invasive Escherichia coli belonging to several serogroups and 13 non-invasive of several serotypes that share the same O antigen was investigated by multilocus enzyme electrophoresis analysis. The invasive strains were isolated in different parts of the world and most of them recovered from dysentery. Twenty-nine electrophoretic types were distinguished and the most invasive strains were found to belong to two major lineages. These results suggested that the invasive ability in these strains has evolved in divergent chromosomal backgrounds, presumably through the horizontal spread of plasmid-borne invasion genes. The maintenance of invasive phenotypes in separate lineages suggests that this ability confers a selective advantage to invasive strains. Copyright (C) 1999 Federation of European Microbiological Societies.

Original language	English (US)
Pages (from-to)	145-151
Number of pages	7
Journal	FEMS Microbiology Letters
Volume	172
Issue number	2
DOIs	https://doi.org/10.1016/S0378-1097(99)00031-2
State	Published - Mar 15 1999

All Science Journal Classification (ASJC) codes

Microbiology
Molecular Biology
Genetics

Access to Document

10.1016/S0378-1097(99)00031-2

Cite this

@article{1b64b56cb4544efc9ba15e6ecc2153eb,

title = "Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups",

abstract = "The genetic relatedness among 96 invasive Escherichia coli belonging to several serogroups and 13 non-invasive of several serotypes that share the same O antigen was investigated by multilocus enzyme electrophoresis analysis. The invasive strains were isolated in different parts of the world and most of them recovered from dysentery. Twenty-nine electrophoretic types were distinguished and the most invasive strains were found to belong to two major lineages. These results suggested that the invasive ability in these strains has evolved in divergent chromosomal backgrounds, presumably through the horizontal spread of plasmid-borne invasion genes. The maintenance of invasive phenotypes in separate lineages suggests that this ability confers a selective advantage to invasive strains. Copyright (C) 1999 Federation of European Microbiological Societies.",

author = "Martinez, {Marina B.} and Whittan, {Thomas S.} and McGraw, {Elizabeth A.} and Josias Rodrigues and Trabulsi, {Luiz R.}",

note = "Funding Information: This work was supported by grants from FAPESP (94/3014-0).",

year = "1999",

month = mar,

day = "15",

doi = "10.1016/S0378-1097(99)00031-2",

language = "English (US)",

volume = "172",

pages = "145--151",

journal = "FEMS Microbiology Letters",

issn = "0378-1097",

publisher = "Oxford University Press",

number = "2",

}

TY - JOUR

T1 - Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups

AU - Martinez, Marina B.

AU - Whittan, Thomas S.

AU - McGraw, Elizabeth A.

AU - Rodrigues, Josias

AU - Trabulsi, Luiz R.

N1 - Funding Information: This work was supported by grants from FAPESP (94/3014-0).

PY - 1999/3/15

Y1 - 1999/3/15

N2 - The genetic relatedness among 96 invasive Escherichia coli belonging to several serogroups and 13 non-invasive of several serotypes that share the same O antigen was investigated by multilocus enzyme electrophoresis analysis. The invasive strains were isolated in different parts of the world and most of them recovered from dysentery. Twenty-nine electrophoretic types were distinguished and the most invasive strains were found to belong to two major lineages. These results suggested that the invasive ability in these strains has evolved in divergent chromosomal backgrounds, presumably through the horizontal spread of plasmid-borne invasion genes. The maintenance of invasive phenotypes in separate lineages suggests that this ability confers a selective advantage to invasive strains. Copyright (C) 1999 Federation of European Microbiological Societies.

AB - The genetic relatedness among 96 invasive Escherichia coli belonging to several serogroups and 13 non-invasive of several serotypes that share the same O antigen was investigated by multilocus enzyme electrophoresis analysis. The invasive strains were isolated in different parts of the world and most of them recovered from dysentery. Twenty-nine electrophoretic types were distinguished and the most invasive strains were found to belong to two major lineages. These results suggested that the invasive ability in these strains has evolved in divergent chromosomal backgrounds, presumably through the horizontal spread of plasmid-borne invasion genes. The maintenance of invasive phenotypes in separate lineages suggests that this ability confers a selective advantage to invasive strains. Copyright (C) 1999 Federation of European Microbiological Societies.

UR - http://www.scopus.com/inward/record.url?scp=0033003883&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033003883&partnerID=8YFLogxK

U2 - 10.1016/S0378-1097(99)00031-2

DO - 10.1016/S0378-1097(99)00031-2

M3 - Article

C2 - 10188242

AN - SCOPUS:0033003883

SN - 0378-1097

VL - 172

SP - 145

EP - 151

JO - FEMS Microbiology Letters

JF - FEMS Microbiology Letters

IS - 2

ER -

Clonal relationship among invasive and non-invasive strains of enteroinvasive Escherichia coli serogroups

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this