TY - JOUR
T1 - Clostridium difficile Colitis
T2 - Factors Associated with Outcome and Assessment of Mortality at a National Level
AU - Stewart, David B.
AU - Hollenbeak, Christopher S.
PY - 2011/9
Y1 - 2011/9
N2 - Background: Previous descriptions of Clostridium difficile colitis (CDC) epidemics may overestimate cost and mortality of CDC. Methods: An analysis of the 2007 Nationwide Inpatient Sample was performed. Patients with CDC (N = 41,207) were compared to a propensity score-matched cohort of patients without CDC. Results: Average length of stay was longer for CDC patients by 5 days (p < 0. 001). Mortality was higher for the CDC cohort (9. 4% vs. 8. 6%; p < 0. 001) though the absolute difference was small. Mean hospital costs were 56% higher for CDC patients (p < 0. 001). Higher odds of death with CDC were associated with small hospitals and self-pay patients. Chronic renal failure and diabetes were associated with lower hospital costs and lower odds of death in the CDC cohort. Conclusions: CDC is not as deadly of a disease as it may be perceived to be at larger hospitals, and mortality was actually unaffected by certain serious comorbidities. CDC is expensive due to a longer hospital stay.
AB - Background: Previous descriptions of Clostridium difficile colitis (CDC) epidemics may overestimate cost and mortality of CDC. Methods: An analysis of the 2007 Nationwide Inpatient Sample was performed. Patients with CDC (N = 41,207) were compared to a propensity score-matched cohort of patients without CDC. Results: Average length of stay was longer for CDC patients by 5 days (p < 0. 001). Mortality was higher for the CDC cohort (9. 4% vs. 8. 6%; p < 0. 001) though the absolute difference was small. Mean hospital costs were 56% higher for CDC patients (p < 0. 001). Higher odds of death with CDC were associated with small hospitals and self-pay patients. Chronic renal failure and diabetes were associated with lower hospital costs and lower odds of death in the CDC cohort. Conclusions: CDC is not as deadly of a disease as it may be perceived to be at larger hospitals, and mortality was actually unaffected by certain serious comorbidities. CDC is expensive due to a longer hospital stay.
UR - http://www.scopus.com/inward/record.url?scp=80051946143&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80051946143&partnerID=8YFLogxK
U2 - 10.1007/s11605-011-1615-6
DO - 10.1007/s11605-011-1615-6
M3 - Article
C2 - 21720924
AN - SCOPUS:80051946143
SN - 1091-255X
VL - 15
SP - 1548
EP - 1555
JO - Journal of Gastrointestinal Surgery
JF - Journal of Gastrointestinal Surgery
IS - 9
ER -
