Coarse-grained optimization-driven design and piecewise linear modeling of synthetic genetic circuits

Keyphrases

• Circuit Structure 100%
• Synthetic Gene Circuits 100%
• Key Barriers 50%
• Media Effectiveness 50%
• Standard Biological Parts 50%
• Toggle Switch 50%
• Biological Parts 50%
• Piecewise-linear Differential Equations 50%
• Circuit Configuration 50%
• Constrained Objective Function 50%
• Half Adder 50%
• Circuit Element 50%
• Maximization-minimization 50%
• Qualitative Knowledge 50%
• Protein Abundance 50%
• Genetic Circuit Design 50%

Engineering

• Binding Site 66%
• Circuit Design 66%
• Input Signal 33%
• Objective Function 33%
• Maximization 33%
• Adders 33%
• Circuit Simulation 33%
• Circuit Element 33%
• Synthetic Biology 33%

Biochemistry, Genetics and Molecular Biology

• Genetics 100%
• Binding Site 28%
• Protein Expression 14%
• Promoter Region 14%