Color Doppler signal detection as a predictor of high grade prostate cancer

M. Ishmail, A. Alexander, L. Gomella, Craig Newschaffer, R. Peterson

Research output: Contribution to journalArticlepeer-review


To investigate the association of color signal detected within prostate cancer and its biologic behavior as assessed by Gleason score. Transrectal sonography with a 7 MHz probe (Acuson, Mountain View, CA) capable of color Doppler imaging was performed in 2718 men (ages 47-72 y) and recorded on videotape for off-line review. Color signal (CDI) detected was grade 0-2+ and compared to the Gleason score (GS) graded ≤4, 5-6 and ≥7 in clinically localized prostate cancer treated by radical prostatectomy in 47. CDI signal detected within cancer was graded 2+ in 60% (17 of 28) of ≥7 tumors, 29% (12 of 42) of 5-6 tumors and 0% (0 of 9) of ≤4 tumors. The grade of color signal may provide a means of distinguishing high grade tumors from low grade tumors.

Original languageEnglish (US)
JournalUltrasound in Medicine and Biology
Issue numberSuppl 1
StatePublished - Jan 1 1997

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Biophysics
  • Acoustics and Ultrasonics


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