TY - JOUR
T1 - Colorectal cancer in inflammatory bowel disease
AU - Krok, Karen
AU - Lichtenstein, Gary R.
PY - 2004/1/1
Y1 - 2004/1/1
N2 - Purpose of review: Patients with inflammatory bowel disease, either Crohn disease or ulcerative colitis, are at an increased risk for developing colorectal carcinoma. Recent findings: Surveillance colonoscopy, although never formally evaluated in a prospective controlled trial, is performed in an effort to reduce this risk. Novel methods of detecting dysplasia are constantly being evaluated, including chromoendoscopy and biomarkers of carcinoma, in an attempt to stratify patients who are at a higher risk of developing high-grade dysplasia or carcinoma. Summary: Because of the potential impact on quality of life and life expectancy, an optimal strategy for reducing the risk of developing colorectal cancer in patients with inflammatory bowel disease needs to be defined.
AB - Purpose of review: Patients with inflammatory bowel disease, either Crohn disease or ulcerative colitis, are at an increased risk for developing colorectal carcinoma. Recent findings: Surveillance colonoscopy, although never formally evaluated in a prospective controlled trial, is performed in an effort to reduce this risk. Novel methods of detecting dysplasia are constantly being evaluated, including chromoendoscopy and biomarkers of carcinoma, in an attempt to stratify patients who are at a higher risk of developing high-grade dysplasia or carcinoma. Summary: Because of the potential impact on quality of life and life expectancy, an optimal strategy for reducing the risk of developing colorectal cancer in patients with inflammatory bowel disease needs to be defined.
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U2 - 10.1097/00001574-200401000-00009
DO - 10.1097/00001574-200401000-00009
M3 - Review article
C2 - 15703619
AN - SCOPUS:4344592401
SN - 0267-1379
VL - 20
SP - 43
EP - 48
JO - Current Opinion in Gastroenterology
JF - Current Opinion in Gastroenterology
IS - 1
ER -