Abstract
We report the ability of a novel combinatorial therapy obtained from nanoparticles of hyperstar polymers encompassing drugs to selectively target triple negative breast cancer (TNBC) cell proliferation through STAT3 and topoisomerase-II pathways. This nano-cocktail was at least two to four fold better than the individual drugs and 6-20 times more selective than the parent drugs.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 16710-16713 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 51 |
| Issue number | 93 |
| DOIs | |
| State | Published - 2015 |
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Catalysis
- Ceramics and Composites
- General Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
