Combined factor V-VIII deficiency: A case report with studies of factor V and VIII activation by thrombin

M. B. Hultin, M. E. Eyster

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A new case of combined factor V-VIII deficiency is reported with in vitro studies of factors V and VIII activation by thrombin. The normal activation of factors V and VIII demonstrated in the patient's plasma and the equivalent levels of factor VIII coagulant activity and coagulant antigen support the hypothesis that a quantitative rather than qualitative defect in factors V and VIII is present in this disorder.

Original languageEnglish (US)
Pages (from-to)983-985
Number of pages3
JournalBlood
Volume58
Issue number5
DOIs
StatePublished - 1981

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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