Combined kidney/bone marrow transplantation

Ron Shapiro; Abdul S. Rao; Paulo Fontes; Adrianna Zeevi; Mark Jordan; Velma P. Scantlebury; Carlos Vivas; H. Albin Gritsch; Robert J. Corry; Francesca Egidi; Maria T. Rugeles; Horacio Rilo; Abdelouahab Aitouche; Anthony J. Demetris; Gayle Rosner; Massimo Trucco; Witold Rybka; William Irish; John J. Fung; Thomas E. Starzl

Combined kidney/bone marrow transplantation

Ron Shapiro, Abdul S. Rao, Paulo Fontes, Adrianna Zeevi, Mark Jordan, Velma P. Scantlebury, Carlos Vivas, H. Albin Gritsch, Robert J. Corry, Francesca Egidi, Maria T. Rugeles, Horacio Rilo, Abdelouahab Aitouche, Anthony J. Demetris, Gayle Rosner, Massimo Trucco, Witold Rybka, William Irish, John J. Fung, Thomas E. Starzl

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Within the past few years, a new conceptual view of transplantation has emerged, based on the observation that renal transplant recipients with extremely long (27-29 years) graft survival all have had evidence of donor cells in their peripheral blood, skin, and lymph nodes. They were thus chimeric. This led to the theory that chimerism is necessary for successful long-term engraftment. It also led to the next logical step of attempting to augment chimerism by transplanting donor bone marrow at the time of organ transplantation. Early reports of combined organ/bone marrow transplantation have suggested that it is safe and is associated with reasonable outcomes. In this paper, we discuss the outcome in the first 30 patients undergoing combined kidney/bone marrow transplantation.

Original language	English (US)
Pages (from-to)	282-287
Number of pages	6
Journal	Dialysis and Transplantation
Volume	25
Issue number	5
State	Published - May 1996

All Science Journal Classification (ASJC) codes

Nephrology
Transplantation

Cite this

@article{48340438ae734c35ae458016e746f86c,

title = "Combined kidney/bone marrow transplantation",

abstract = "Within the past few years, a new conceptual view of transplantation has emerged, based on the observation that renal transplant recipients with extremely long (27-29 years) graft survival all have had evidence of donor cells in their peripheral blood, skin, and lymph nodes. They were thus chimeric. This led to the theory that chimerism is necessary for successful long-term engraftment. It also led to the next logical step of attempting to augment chimerism by transplanting donor bone marrow at the time of organ transplantation. Early reports of combined organ/bone marrow transplantation have suggested that it is safe and is associated with reasonable outcomes. In this paper, we discuss the outcome in the first 30 patients undergoing combined kidney/bone marrow transplantation.",

author = "Ron Shapiro and Rao, {Abdul S.} and Paulo Fontes and Adrianna Zeevi and Mark Jordan and Scantlebury, {Velma P.} and Carlos Vivas and Gritsch, {H. Albin} and Corry, {Robert J.} and Francesca Egidi and Rugeles, {Maria T.} and Horacio Rilo and Abdelouahab Aitouche and Demetris, {Anthony J.} and Gayle Rosner and Massimo Trucco and Witold Rybka and William Irish and Fung, {John J.} and Starzl, {Thomas E.}",

year = "1996",

month = may,

language = "English (US)",

volume = "25",

pages = "282--287",

journal = "Dialysis and Transplantation",

issn = "0090-2934",

publisher = "John Wiley & Sons Inc.",

number = "5",

}

TY - JOUR

T1 - Combined kidney/bone marrow transplantation

AU - Shapiro, Ron

AU - Rao, Abdul S.

AU - Fontes, Paulo

AU - Zeevi, Adrianna

AU - Jordan, Mark

AU - Scantlebury, Velma P.

AU - Vivas, Carlos

AU - Gritsch, H. Albin

AU - Corry, Robert J.

AU - Egidi, Francesca

AU - Rugeles, Maria T.

AU - Rilo, Horacio

AU - Aitouche, Abdelouahab

AU - Demetris, Anthony J.

AU - Rosner, Gayle

AU - Trucco, Massimo

AU - Rybka, Witold

AU - Irish, William

AU - Fung, John J.

AU - Starzl, Thomas E.

PY - 1996/5

Y1 - 1996/5

N2 - Within the past few years, a new conceptual view of transplantation has emerged, based on the observation that renal transplant recipients with extremely long (27-29 years) graft survival all have had evidence of donor cells in their peripheral blood, skin, and lymph nodes. They were thus chimeric. This led to the theory that chimerism is necessary for successful long-term engraftment. It also led to the next logical step of attempting to augment chimerism by transplanting donor bone marrow at the time of organ transplantation. Early reports of combined organ/bone marrow transplantation have suggested that it is safe and is associated with reasonable outcomes. In this paper, we discuss the outcome in the first 30 patients undergoing combined kidney/bone marrow transplantation.

AB - Within the past few years, a new conceptual view of transplantation has emerged, based on the observation that renal transplant recipients with extremely long (27-29 years) graft survival all have had evidence of donor cells in their peripheral blood, skin, and lymph nodes. They were thus chimeric. This led to the theory that chimerism is necessary for successful long-term engraftment. It also led to the next logical step of attempting to augment chimerism by transplanting donor bone marrow at the time of organ transplantation. Early reports of combined organ/bone marrow transplantation have suggested that it is safe and is associated with reasonable outcomes. In this paper, we discuss the outcome in the first 30 patients undergoing combined kidney/bone marrow transplantation.

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M3 - Article

AN - SCOPUS:15844366021

SN - 0090-2934

VL - 25

SP - 282

EP - 287

JO - Dialysis and Transplantation

JF - Dialysis and Transplantation

IS - 5

ER -

Combined kidney/bone marrow transplantation

Abstract

All Science Journal Classification (ASJC) codes

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