TY - JOUR
T1 - Combined Merkel cell carcinoma and atypical fibroxanthoma
AU - Youker, Summer R.
AU - Billingsley, Elizabeth M.
PY - 2005/2
Y1 - 2005/2
N2 - Background: Although there are reports of squamous cell carcinoma arising within and adjacent to Merkel cell carcinoma, and one report of an atypical fibroxanthoma-like tumor arising in an irradiated recurrent Merkel cell carcinoma, there have previously been no reports of an immunohistochemically verified atypical fibroxanthoma occurring in conjunction with a Merkel cell carcinoma. Objective: We report on a neoplasm with distinct features of both Merkel cell carcinoma and atypical fibroxanthoma. Methods: Histologic and immunohistochemical evaluations were performed. Results: Our results verify the finding of a combined Merkel cell carcinoma and atypical fibroxanthoma. Conclusion: This case is an interesting and unusual combination of tumors. The origin of the Merkel cell carcinoma is revisited. Debated origins include neuroendocrine, epithelial, and pleuripotent stem cell.
AB - Background: Although there are reports of squamous cell carcinoma arising within and adjacent to Merkel cell carcinoma, and one report of an atypical fibroxanthoma-like tumor arising in an irradiated recurrent Merkel cell carcinoma, there have previously been no reports of an immunohistochemically verified atypical fibroxanthoma occurring in conjunction with a Merkel cell carcinoma. Objective: We report on a neoplasm with distinct features of both Merkel cell carcinoma and atypical fibroxanthoma. Methods: Histologic and immunohistochemical evaluations were performed. Results: Our results verify the finding of a combined Merkel cell carcinoma and atypical fibroxanthoma. Conclusion: This case is an interesting and unusual combination of tumors. The origin of the Merkel cell carcinoma is revisited. Debated origins include neuroendocrine, epithelial, and pleuripotent stem cell.
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U2 - 10.1007/s10227-005-0024-4
DO - 10.1007/s10227-005-0024-4
M3 - Article
C2 - 16208439
AN - SCOPUS:29144536632
SN - 1203-4754
VL - 9
SP - 6
EP - 9
JO - Journal of Cutaneous Medicine and Surgery
JF - Journal of Cutaneous Medicine and Surgery
IS - 1
ER -