Abstract
Background: Although there are reports of squamous cell carcinoma arising within and adjacent to Merkel cell carcinoma, and one report of an atypical fibroxanthoma-like tumor arising in an irradiated recurrent Merkel cell carcinoma, there have previously been no reports of an immunohistochemically verified atypical fibroxanthoma occurring in conjunction with a Merkel cell carcinoma. Objective: We report on a neoplasm with distinct features of both Merkel cell carcinoma and atypical fibroxanthoma. Methods: Histologic and immunohistochemical evaluations were performed. Results: Our results verify the finding of a combined Merkel cell carcinoma and atypical fibroxanthoma. Conclusion: This case is an interesting and unusual combination of tumors. The origin of the Merkel cell carcinoma is revisited. Debated origins include neuroendocrine, epithelial, and pleuripotent stem cell.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 6-9 |
| Number of pages | 4 |
| Journal | Journal of Cutaneous Medicine and Surgery |
| Volume | 9 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 2005 |
All Science Journal Classification (ASJC) codes
- Surgery
- Dermatology
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