Complex modular architecture around a simple toolkit of wing pattern genes

Steven M. Van Belleghem; Pasi Rastas; Alexie Papanicolaou; Simon H. Martin; Carlos F. Arias; Megan A. Supple; Joseph J. Hanly; James Mallet; James J. Lewis; Heather M. Hines; Mayte Ruiz; Camilo Salazar; Mauricio Linares; Gilson R.P. Moreira; Chris D. Jiggins; Brian A. Counterman; W. Owen McMillan; Riccardo Papa

doi:10.1038/s41559-016-0052

Complex modular architecture around a simple toolkit of wing pattern genes

Steven M. Van Belleghem, Pasi Rastas, Alexie Papanicolaou, Simon H. Martin, Carlos F. Arias, Megan A. Supple, Joseph J. Hanly, James Mallet, James J. Lewis, Heather M. Hines, Mayte Ruiz, Camilo Salazar, Mauricio Linares, Gilson R.P. Moreira, Chris D. Jiggins, Brian A. Counterman, W. Owen McMillan, Riccardo Papa

Research output: Contribution to journal › Article › peer-review

141 Scopus citations

Abstract

Identifying the genomic changes that control morphological variation and understanding how they generate diversity is a major goal of evolutionary biology. In Heliconius butterflies, a small number of genes control the development of diverse wing colour patterns. Here, we used full-genome sequencing of individuals across the Heliconius erato radiation and closely related species to characterize genomic variation associated with wing pattern diversity. We show that variation around colour pattern genes is highly modular, with narrow genomic intervals associated with specific differences in colour and pattern. This modular architecture explains the diversity of colour patterns and provides a flexible mechanism for rapid morphological diversification.

Original language	English (US)
Article number	0052
Journal	Nature Ecology and Evolution
Volume	1
Issue number	3
DOIs	https://doi.org/10.1038/s41559-016-0052
State	Published - Jan 30 2017

All Science Journal Classification (ASJC) codes

Ecology, Evolution, Behavior and Systematics
Ecology

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Van Belleghem, S. M., Rastas, P., Papanicolaou, A., Martin, S. H., Arias, C. F., Supple, M. A., Hanly, J. J., Mallet, J., Lewis, J. J., Hines, H. M., Ruiz, M., Salazar, C., Linares, M., Moreira, G. R. P., Jiggins, C. D., Counterman, B. A., McMillan, W. O., & Papa, R. (2017). Complex modular architecture around a simple toolkit of wing pattern genes. Nature Ecology and Evolution, 1(3), Article 0052. https://doi.org/10.1038/s41559-016-0052

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abstract = "Identifying the genomic changes that control morphological variation and understanding how they generate diversity is a major goal of evolutionary biology. In Heliconius butterflies, a small number of genes control the development of diverse wing colour patterns. Here, we used full-genome sequencing of individuals across the Heliconius erato radiation and closely related species to characterize genomic variation associated with wing pattern diversity. We show that variation around colour pattern genes is highly modular, with narrow genomic intervals associated with specific differences in colour and pattern. This modular architecture explains the diversity of colour patterns and provides a flexible mechanism for rapid morphological diversification.",

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doi = "10.1038/s41559-016-0052",

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Van Belleghem, SM, Rastas, P, Papanicolaou, A, Martin, SH, Arias, CF, Supple, MA, Hanly, JJ, Mallet, J, Lewis, JJ, Hines, HM, Ruiz, M, Salazar, C, Linares, M, Moreira, GRP, Jiggins, CD, Counterman, BA, McMillan, WO & Papa, R 2017, 'Complex modular architecture around a simple toolkit of wing pattern genes', Nature Ecology and Evolution, vol. 1, no. 3, 0052. https://doi.org/10.1038/s41559-016-0052

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AU - Rastas, Pasi

AU - Papanicolaou, Alexie

AU - Martin, Simon H.

AU - Arias, Carlos F.

AU - Supple, Megan A.

AU - Hanly, Joseph J.

AU - Mallet, James

AU - Lewis, James J.

AU - Hines, Heather M.

AU - Ruiz, Mayte

AU - Salazar, Camilo

AU - Linares, Mauricio

AU - Moreira, Gilson R.P.

AU - Jiggins, Chris D.

AU - Counterman, Brian A.

AU - McMillan, W. Owen

AU - Papa, Riccardo

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AB - Identifying the genomic changes that control morphological variation and understanding how they generate diversity is a major goal of evolutionary biology. In Heliconius butterflies, a small number of genes control the development of diverse wing colour patterns. Here, we used full-genome sequencing of individuals across the Heliconius erato radiation and closely related species to characterize genomic variation associated with wing pattern diversity. We show that variation around colour pattern genes is highly modular, with narrow genomic intervals associated with specific differences in colour and pattern. This modular architecture explains the diversity of colour patterns and provides a flexible mechanism for rapid morphological diversification.

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Complex modular architecture around a simple toolkit of wing pattern genes

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