Abstract
Surface based mass spectrometric approaches fill an important niche in the mass analysis portfolio of tools. The particular niche depends on both the underlying physics and chemistry of molecule ejection as well as experimental characteristics. In this article, we use molecular dynamics computer simulations to elucidate the fundamental processes giving rise to ejection of organic molecules in atomic and cluster secondary ion mass spectrometry (SIMS), massive cluster impact (MCI) mass spectrometry, and matrix-assisted laser desorption ionization (MALDI) mass spectrometry. This review is aimed at graduate students and experimental researchers.
Original language | English (US) |
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Pages (from-to) | 289-315 |
Number of pages | 27 |
Journal | Mass Spectrometry Reviews |
Volume | 27 |
Issue number | 4 |
DOIs | |
State | Published - Jul 2008 |
All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Condensed Matter Physics
- General Biochemistry, Genetics and Molecular Biology
- Spectroscopy