TY - JOUR
T1 - Computer-assisted endoscopic coronary artery bypass anastomoses
T2 - A chronic animal study
AU - Stephenson, Edward
AU - Ducko, Christopher T.
AU - Sankholkar, Sachin
AU - Hoenicke, Eric M.
AU - Prophet, G. Allen
AU - Damiano, Ralph J.
N1 - Funding Information:
The work described in this report was supported by a grant from Computer Motion Inc. Sachin Sankholkar is an employee of Computer Motion Inc.
PY - 1999/9
Y1 - 1999/9
N2 - Background. With traditional instruments, endoscopic coronary artery bypass grafting (ECABG) has not been possible. This study was designed to determine the feasibility of using a robotically-assisted microsurgical system to perform ECABG in a chronic animal model. Methods. Nine calves were placed on cardiopulmonary bypass after harvesting the left internal mammary artery (LIMA). Subxiphoid endoscopic ports (2 instrument, 1 camera) were placed, and a robotic system was used to perform ECABG between the LIMA and left anterior descending coronary artery. LIMA graft flow (LIMA(Q)) was measured. Animals were sacrificed at 1 month, and hearts underwent angiographic and histologic analyses. Results. Acute graft patency was 89% (8/9). Two animals died suddenly within the first 48 hours. There was no significant difference in mean acute and chronic (n = 6) LIMA(Q) (40.9 ± 4.7 and 38.5 ± 5.0 ml/min, respectively). Survivors had an angiographic patency rate of 100% (6/6), confirmed by histology. Conclusions. This study shows that ECABG is feasible in a chronic animal model with excellent results.
AB - Background. With traditional instruments, endoscopic coronary artery bypass grafting (ECABG) has not been possible. This study was designed to determine the feasibility of using a robotically-assisted microsurgical system to perform ECABG in a chronic animal model. Methods. Nine calves were placed on cardiopulmonary bypass after harvesting the left internal mammary artery (LIMA). Subxiphoid endoscopic ports (2 instrument, 1 camera) were placed, and a robotic system was used to perform ECABG between the LIMA and left anterior descending coronary artery. LIMA graft flow (LIMA(Q)) was measured. Animals were sacrificed at 1 month, and hearts underwent angiographic and histologic analyses. Results. Acute graft patency was 89% (8/9). Two animals died suddenly within the first 48 hours. There was no significant difference in mean acute and chronic (n = 6) LIMA(Q) (40.9 ± 4.7 and 38.5 ± 5.0 ml/min, respectively). Survivors had an angiographic patency rate of 100% (6/6), confirmed by histology. Conclusions. This study shows that ECABG is feasible in a chronic animal model with excellent results.
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U2 - 10.1016/S0003-4975(99)00794-8
DO - 10.1016/S0003-4975(99)00794-8
M3 - Article
C2 - 10509971
AN - SCOPUS:0345580686
SN - 0003-4975
VL - 68
SP - 838
EP - 843
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 3
ER -