Abstract
We consider a free boundary problem modeling tumor growth where the model equations include a diffusion equation for the nutrient concentration and the Stokes equation for the proliferation of tumor cells. For any positive radius R, it is known that there exists a unique radially symmetric stationary solution. The proliferation rate μ and the cell-to-cell adhesiveness γ are two parameters for characterizing "aggressiveness" of the tumor. We compute symmetry-breaking bifurcation branches of solutions by studying a polynomial discretization of the system. By tracking the discretized system, we numerically verified a sequence of μγ symmetry breaking bifurcation branches. Furthermore, we study the stability of both radially symmetric and radially asymmetric stationary solutions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 326-334 |
| Number of pages | 9 |
| Journal | Journal of Computational and Applied Mathematics |
| Volume | 237 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2013 |
All Science Journal Classification (ASJC) codes
- Computational Mathematics
- Applied Mathematics
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