Consequences of expressing mutants of the hemochromatosis gene (HFE) into a human neuronal cell line lacking endogenous HFE

Keyphrases

• Hemochromatosis Gene 100%
• H63D 100%
• HFE Gene 100%
• C282Y 100%
• Signal Transduction Pathway 33%
• Lipid Peroxidation 33%
• IRP1 33%
• Oxidative Stress 33%
• Targeted Gene 33%
• Hemochromatosis 33%
• Protein Activity 33%
• Human Neuroblastoma 33%
• Neurodegenerative Diseases 33%
• Clinical Consequences 33%
• Protein Oxidation 33%
• Stable Cell Line 33%
• Iron Chelation 33%
• Mitochondrial Membrane Potential 33%
• Unique Effects 33%
• Genetic Modifiers 33%
• Mutant Forms 33%
• Uncommon mutation 33%
• C282Y mutation 33%
• Stress Agents 33%

Biochemistry, Genetics and Molecular Biology

• HFE (Gene) 100%
• Wild Type 66%
• Genetics 33%
• Signal Transduction 33%
• DNA Microarray 33%
• Oxidative Stress 33%
• Alpha Oxidation 33%
• Stable Cell 33%
• Iron Chelation 33%
• Lipid Peroxidation 33%
• Iron Poisoning 33%
• Iron Overload 33%
• Mitochondrial Membrane Potential 33%

Neuroscience

• Cell Line 100%
• Neuroblastoma 33%
• Neurodegenerative Disorder 33%
• Oxidative Stress 33%
• DNA Microarray 33%
• Mitochondrial Membrane Potential 33%
• Lipid Peroxidation 33%
• Signal Transduction Pathway 33%
• Iron Regulatory Factor 33%