Conserved noncoding sequences are reliable guides to regulatory elements

R. C. Hardison

doi:10.1016/S0168-9525(00)02081-3

Conserved noncoding sequences are reliable guides to regulatory elements

R. C. Hardison

Research output: Contribution to journal › Short survey › peer-review

346 Scopus citations

Abstract

A 'working draft' of the human genome sequence is now available. Comparisons with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective comparison differs among various loci. Copyright (C) 2000 Elsevier Science Ltd.

Original language	English (US)
Pages (from-to)	369-372
Number of pages	4
Journal	Trends in Genetics
Volume	16
Issue number	9
DOIs	https://doi.org/10.1016/S0168-9525(00)02081-3
State	Published - Sep 1 2000

All Science Journal Classification (ASJC) codes

Genetics

Access to Document

10.1016/S0168-9525(00)02081-3

Cite this

@article{706b128858ea4ad797f199445f56e750,

title = "Conserved noncoding sequences are reliable guides to regulatory elements",

abstract = "A 'working draft' of the human genome sequence is now available. Comparisons with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective comparison differs among various loci. Copyright (C) 2000 Elsevier Science Ltd.",

author = "Hardison, {R. C.}",

note = "Funding Information: I thank W. Miller, D. Sch{\"u}beler, M. Bulger and the reviewers for helpful comments. Work from this laboratory was supported by PHS grants DK27635, LM05110 and LM05773. ",

year = "2000",

month = sep,

day = "1",

doi = "10.1016/S0168-9525(00)02081-3",

language = "English (US)",

volume = "16",

pages = "369--372",

journal = "Trends in Genetics",

issn = "0168-9525",

publisher = "Elsevier Ltd",

number = "9",

}

TY - JOUR

T1 - Conserved noncoding sequences are reliable guides to regulatory elements

AU - Hardison, R. C.

N1 - Funding Information: I thank W. Miller, D. Schübeler, M. Bulger and the reviewers for helpful comments. Work from this laboratory was supported by PHS grants DK27635, LM05110 and LM05773.

PY - 2000/9/1

Y1 - 2000/9/1

N2 - A 'working draft' of the human genome sequence is now available. Comparisons with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective comparison differs among various loci. Copyright (C) 2000 Elsevier Science Ltd.

AB - A 'working draft' of the human genome sequence is now available. Comparisons with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective comparison differs among various loci. Copyright (C) 2000 Elsevier Science Ltd.

UR - http://www.scopus.com/inward/record.url?scp=0034284481&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034284481&partnerID=8YFLogxK

U2 - 10.1016/S0168-9525(00)02081-3

DO - 10.1016/S0168-9525(00)02081-3

M3 - Short survey

C2 - 10973062

AN - SCOPUS:0034284481

SN - 0168-9525

VL - 16

SP - 369

EP - 372

JO - Trends in Genetics

JF - Trends in Genetics

IS - 9

ER -

Conserved noncoding sequences are reliable guides to regulatory elements

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this