Conserved noncoding sequences are reliable guides to regulatory elements

R. C. Hardison

Research output: Contribution to journalShort surveypeer-review

344 Scopus citations


A 'working draft' of the human genome sequence is now available. Comparisons with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective comparison differs among various loci. Copyright (C) 2000 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)369-372
Number of pages4
JournalTrends in Genetics
Issue number9
StatePublished - Sep 1 2000

All Science Journal Classification (ASJC) codes

  • Genetics


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