Construction of β-haloenamides via direct copper-promoted coupling of lactams with 2-chloro and 2-bromo vinyliodides

Cuixiang Sun; Jason E. Camp; Steven M. Weinreb

doi:10.1021/ol060093a

Construction of β-haloenamides via direct copper-promoted coupling of lactams with 2-chloro and 2-bromo vinyliodides

Cuixiang Sun, Jason E. Camp, Steven M. Weinreb

Chemistry

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

Cu(I)-catalyzed coupling of lactams with (E)-2-chlorovinyliodides or (E)-2-bromovinyliodides produces the corresponding β-haloenamides in moderate to excellent yields.

Original language	English (US)
Pages (from-to)	1779-1781
Number of pages	3
Journal	Organic Letters
Volume	8
Issue number	9
DOIs	https://doi.org/10.1021/ol060093a
State	Published - Apr 27 2006

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol060093a

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title = "Construction of β-haloenamides via direct copper-promoted coupling of lactams with 2-chloro and 2-bromo vinyliodides",

abstract = "Cu(I)-catalyzed coupling of lactams with (E)-2-chlorovinyliodides or (E)-2-bromovinyliodides produces the corresponding β-haloenamides in moderate to excellent yields.",

author = "Cuixiang Sun and Camp, {Jason E.} and Weinreb, {Steven M.}",

year = "2006",

month = apr,

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doi = "10.1021/ol060093a",

language = "English (US)",

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journal = "Organic Letters",

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publisher = "American Chemical Society",

number = "9",

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T1 - Construction of β-haloenamides via direct copper-promoted coupling of lactams with 2-chloro and 2-bromo vinyliodides

AU - Sun, Cuixiang

AU - Camp, Jason E.

AU - Weinreb, Steven M.

PY - 2006/4/27

Y1 - 2006/4/27

N2 - Cu(I)-catalyzed coupling of lactams with (E)-2-chlorovinyliodides or (E)-2-bromovinyliodides produces the corresponding β-haloenamides in moderate to excellent yields.

AB - Cu(I)-catalyzed coupling of lactams with (E)-2-chlorovinyliodides or (E)-2-bromovinyliodides produces the corresponding β-haloenamides in moderate to excellent yields.

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U2 - 10.1021/ol060093a

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SN - 1523-7060

VL - 8

SP - 1779

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JO - Organic Letters

JF - Organic Letters

IS - 9

ER -

Construction of β-haloenamides via direct copper-promoted coupling of lactams with 2-chloro and 2-bromo vinyliodides

Abstract

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