@inproceedings{297f94b2da31449da750634103961d93,
title = "Continuous estimates of index of intracranial compliance derived from intracranial pressure recordings",
abstract = "The purpose of this study is to explore the development of a method to derive continuous estimates of an index of intracranial compliance from recordings of intracranial pressure (ICP). The proposed index, percent change of compliance per mmHg of ICP (%CC/mmHg), is based on two assumptions: 1) the pressure-volume characteristic of the craniospinal sac can be linearized for small perturbations about an equilibrium; and 2) during a brief interval in which these perturbations occur the pathophysiologic state of the craniospinal sac does not significantly change. Values of %CC/mmHg were derived from laboratory recordings of ICP obtained from four bovine preparations and found to be strongly inversely correlated with ICP with all r-values greater than 0.97. To date three clinical cases also demonstrate the same inverse relationship between %CC/mmHg and ICP. This index may be of value as an independent check on the D.C. drift of the transducer and in patient management during long term monitoring.",
author = "Pasley, {Richard L.} and Leffler, {Charles W.} and Shelly Timmons and Gregory Stidham and Daley, {Michael L.}",
year = "1999",
month = dec,
day = "1",
language = "English (US)",
isbn = "0780356756",
series = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
publisher = "IEEE",
booktitle = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
note = "Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) ; Conference date: 13-10-1999 Through 16-10-1999",
}