Abstract
Cutaneous malignancies may spread to underlying nerves, a process known as perineural invasion (PNI). We report a patient who was found to have PNI presenting as a cranial polyneuropathy on the contralateral side of the face many years after the resection of a squamous cell carcinoma. All diagnostic testing was unrevealing until nerve biopsy was performed. This emphasizes the long asymptomatic period between treatment of a cutaneous malignancy and detection of PNI, and the development of PNI at a site distant from the original malignancy. Biopsy of a clinically involved nerve may permit diagnosis of PNI when other studies are normal.
Original language | English (US) |
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Pages (from-to) | 132-136 |
Number of pages | 5 |
Journal | Journal of clinical neuromuscular disease |
Volume | 11 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2010 |
All Science Journal Classification (ASJC) codes
- Neurology
- Clinical Neurology