Cooperativity between the polyamine pathway and HER-2neu in transformation of human mammary epithelial cells in culture: Role of the MAPK pathway

Keyphrases

• Mitogen-activated Protein Kinase 100%
• Cells in Culture 100%
• Ornithine Decarboxylase 100%
• Cooperativity 100%
• Polyamine Pathway 100%
• Human Mammary Epithelial Cells 100%
• Overexpression 80%
• Differentiating Factors 60%
• Epidermal Growth Factor 40%
• MCF10A Cells 40%
• Overexpressing 20%
• Phosphorylation 20%
• Chemoprevention 20%
• Kinase Cascade 20%
• New Targets 20%
• Cell Transformation 20%
• Polyamines 20%
• Polyamine Biosynthesis 20%
• Anchorage-independent Growth 20%
• Human Breast Cancer 20%
• Epithelial Cell Line 20%
• Liquid Culture 20%
• MAPK Activation 20%
• Rate-limiting Enzyme 20%
• Biosynthetic Potential 20%
• Stress-activated Protein Kinase 20%
• Clonogenicity 20%
• MAPK Phosphorylation 20%
• Mammary Cells 20%
• MCF10A 20%

Biochemistry, Genetics and Molecular Biology

• Cooperation 100%
• Mitogen-Activated Protein Kinase 100%
• Ornithine Decarboxylase 100%
• Epidermal Growth Factor 40%
• Enzyme 20%
• In Vivo Study 20%
• Anabolism 20%
• Isoform 20%
• Mediator 20%
• Anchorage Independent Growth 20%
• Cell Transformation 20%
• C-Jun N-Terminal Kinases 20%
• Clonogenesis 20%