Correction to: A Readily Scalable, Clinically Demonstrated, Antibiofouling Zwitterionic Surface Treatment for Implantable Medical Devices (Advanced Materials, (2022), 34, 20, 10.1002/adma.202200254)

Adv. Mater. 2022, 34, 2200254 DOI: 10.1002/adma.202200254 Concerns were raised by a third party regarding the Live/Dead staining micrographs for the PDMS and Coated-PDMS (15 mg mL⁻¹) groups at 72 hours in Figure 5d, which appeared to depict overlapping microscopic fields. Upon review of the original files, the authors confirmed that both images had, in error, been captured from the same sample. As the comprehensive set of original raw images could not be retrieved, the authors repeated the experiment using the original protocol described in the manuscript, and acquired images using a Keyence microscope (BZ-X700 Series, USA). The newly obtained data are consistent with the original findings, and the study's analyses and conclusions remain unchanged. The new micrographs are presented in the corrected Figure 5 below. The authors sincerely regret this oversight. Corrected Figure 5: Figure 5. Assessment of the cytotoxicity and hemolysis of PFPA-PSB. a) Assessing the cytotoxicity of uncross-linked PSB by adding a desirable amount of the polymer to the cell culture media of cultured monolayer NIH/3T3 fibroblast cells and measuring the metabolic activity of cells using the MTT assay. Fluorescent intensity shows that the cells, regardless of the PSB concentration (up to 1600 µg mL⁻¹) are able to metabolize the cell membranepermeable tetrazolium dye MTT, which attests to the insignificant effect of PSB on the cell viability. b) Live/dead staining of the monolayer fibroblast cells cultured in the presence of uncross-linked PSB shows a 100% viability of cells within 72 h. The controls show the cells cultured in the absence of PSB. The scale bar is 100 µm. c) The cytotoxicity of cross-linked PSB was investigated by applying the treatment on PDMS discs, followed by incubating the discs in the cell culture media of cultured monolayer fibroblast cells. The metabolic activity of the cells does not show any significant difference with the PSB-free control. d) Live/dead staining of the fibroblast cells cultured in the presence of cross-linked PSB shows that almost no cell is compromised compared to the PSB-free controls. The scale bar is 100 µm. e) Effect of uncross-linked PSB on the RBCs, shown by the optical images of Eppendorf tubes containing varying concentrations of PFPA-PSB in heparinized human whole blood after centrifuging from which f) the hemolysis percentages of RBCs are calculated. Compared to the positive control (PC, Triton X-100), the uncross-linked PFPA-PSB results in ≤6% hemolysis at ≤10 mg mL⁻¹. Accordingly, uncross-linked and cross-linked PSB are both non-toxic for the cells, rendering this material suitable for coating medical devices that are in contact with cells.