TY - JOUR
T1 - Craniofacial growth in apert syndrome as measured by finite-element scaling analysis
AU - Richtsmeier, Joan T.
PY - 1988
Y1 - 1988
N2 - A new tool for the study of biological form change is applied in a comparison of craniofacial growth in normal children and those affected with Apert syndrome. Using finite-element scaling analysis, the magnitude of size change during postnatal growth in the Apert sample was determined to be generally less than normal, and the magnitude of shape change was generally greater than normal. No consistent, statistically significant, alteration from normal growth was defined in the Apert sample, however. There appears to be no consistent effect on general cell and tissue proliferation in Apert syndrome. Rather, specific subpopulations of cells and tissues may be affected differentially over time.
AB - A new tool for the study of biological form change is applied in a comparison of craniofacial growth in normal children and those affected with Apert syndrome. Using finite-element scaling analysis, the magnitude of size change during postnatal growth in the Apert sample was determined to be generally less than normal, and the magnitude of shape change was generally greater than normal. No consistent, statistically significant, alteration from normal growth was defined in the Apert sample, however. There appears to be no consistent effect on general cell and tissue proliferation in Apert syndrome. Rather, specific subpopulations of cells and tissues may be affected differentially over time.
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U2 - 10.1159/000146614
DO - 10.1159/000146614
M3 - Article
C2 - 3213406
AN - SCOPUS:0023788080
SN - 1422-6405
VL - 133
SP - 50
EP - 56
JO - Cells Tissues Organs
JF - Cells Tissues Organs
IS - 1
ER -