CRISPR-Cas Systems: RNA-mediated adaptive immunity in bacteria and archaea

Rodolphe Barrangou, John van der Oost

Research output: Book/ReportBook

19 Scopus citations


CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.

Original languageEnglish (US)
PublisherSpringer Berlin Heidelberg
Number of pages299
ISBN (Electronic)9783642346576
ISBN (Print)9783642346569
StatePublished - Jan 1 2013

All Science Journal Classification (ASJC) codes

  • General Immunology and Microbiology


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