TY - JOUR
T1 - CT colonography
T2 - Effect of computer-aided detection of colonic polyps as a second and concurrent reader for general radiologists with moderate experience in CT colonography
AU - Mang, Thomas
AU - Bogoni, Luca
AU - Anand, Vikram X.
AU - Chandra, Dass
AU - Curtin, Andrew J.
AU - Lev-Toaff, Anna S.
AU - Hermosillo, Gerardo
AU - Noah, Ralph
AU - Raykar, Vikas
AU - Salganicoff, Marcos
AU - Shaw, Robert
AU - Summerton, Susan
AU - Tappouni, Rafel F.R.
AU - Ringel, Helmut
AU - Weber, Michael
AU - Wolf, Matthias
AU - Obuchowski, Nancy A.
PY - 2014/7
Y1 - 2014/7
N2 - Objectives: To assess the effectiveness of computer-aided detection (CAD) as a second reader or concurrent reader in helping radiologists who are moderately experienced in computed tomographic colonography (CTC) to detect colorectal polyps. Methods: Seventy CTC datasets (34 patients: 66 polyps ≥6 mm; 36 patients: no abnormalities) were retrospectively reviewed by seven radiologists with moderate CTC experience. After primary unassisted evaluation, a CAD second read and, after a time interval of ≥4 weeks, a CAD concurrent read were performed. Areas under the receiver operating characteristic (ROC) curve (AUC), along with per-segment, per-polyp and per-patient sensitivities, and also reading times, were calculated for each reader with and without CAD. Results: Of seven readers, 86 % and 71 % achieved a higher accuracy (segment-level AUC) when using CAD as second and concurrent reader respectively. Average segment-level AUCs with second and concurrent CAD (0.853 and 0.864) were significantly greater (p<0.0001) than average AUC in the unaided evaluation (0.781). Per-segment, per-polyp, and per-patient sensitivities for polyps ≥6 mm were significantly higher in both CAD reading paradigms compared with unaided evaluation. Second-read CAD reduced readers' average segment and patient specificity by 0.007 and 0.036 (p=0.005 and 0.011), respectively. Conclusions: CAD significantly improves the sensitivities of radiologists moderately experienced in CTC for polyp detection, both as second reader and concurrent reader. Key Points: • CAD helps radiologists with moderate CTC experience to detect polyps ≥6 mm. • Second and concurrent read CAD increase the radiologist's sensitivity for detecting polyps ≥6 mm. • Second read CAD slightly decreases specificity compared with an unassisted read. • Concurrent read CAD is significantly more time-efficient than second read CAD.
AB - Objectives: To assess the effectiveness of computer-aided detection (CAD) as a second reader or concurrent reader in helping radiologists who are moderately experienced in computed tomographic colonography (CTC) to detect colorectal polyps. Methods: Seventy CTC datasets (34 patients: 66 polyps ≥6 mm; 36 patients: no abnormalities) were retrospectively reviewed by seven radiologists with moderate CTC experience. After primary unassisted evaluation, a CAD second read and, after a time interval of ≥4 weeks, a CAD concurrent read were performed. Areas under the receiver operating characteristic (ROC) curve (AUC), along with per-segment, per-polyp and per-patient sensitivities, and also reading times, were calculated for each reader with and without CAD. Results: Of seven readers, 86 % and 71 % achieved a higher accuracy (segment-level AUC) when using CAD as second and concurrent reader respectively. Average segment-level AUCs with second and concurrent CAD (0.853 and 0.864) were significantly greater (p<0.0001) than average AUC in the unaided evaluation (0.781). Per-segment, per-polyp, and per-patient sensitivities for polyps ≥6 mm were significantly higher in both CAD reading paradigms compared with unaided evaluation. Second-read CAD reduced readers' average segment and patient specificity by 0.007 and 0.036 (p=0.005 and 0.011), respectively. Conclusions: CAD significantly improves the sensitivities of radiologists moderately experienced in CTC for polyp detection, both as second reader and concurrent reader. Key Points: • CAD helps radiologists with moderate CTC experience to detect polyps ≥6 mm. • Second and concurrent read CAD increase the radiologist's sensitivity for detecting polyps ≥6 mm. • Second read CAD slightly decreases specificity compared with an unassisted read. • Concurrent read CAD is significantly more time-efficient than second read CAD.
UR - https://www.scopus.com/pages/publications/84902376798
UR - https://www.scopus.com/pages/publications/84902376798#tab=citedBy
U2 - 10.1007/s00330-014-3158-1
DO - 10.1007/s00330-014-3158-1
M3 - Article
C2 - 24816931
AN - SCOPUS:84902376798
SN - 0938-7994
VL - 24
SP - 1466
EP - 1476
JO - European Radiology
JF - European Radiology
IS - 7
ER -