TY - JOUR
T1 - Culture of exoerythrocytic stages of the malaria parasites Plasmodium falciparum and Plasmodium vivax.
AU - Cui, Liwang
AU - Trongnipatt, Namtip
AU - Sattabongkot, Jetsumon
AU - Udomsangpetch, Rachanee
PY - 2009
Y1 - 2009
N2 - The two most prevalent human malaria parasites, Plasmodium falciparum and Plasmodium vivax, cause the majority of malaria-related morbidity and mortality. Compared with our knowledge about the erythrocytic stages, we understand little about the liver exoerythrocytic (EE) stages of the human malaria parasites. Our recent development of a hepatocyte line from normal human liver tissue is crucial for successful culturing of the liver stages of both P. falciparum and P. vivax. This technical advancement should be an important tool for directly studying developmental biology of the EE stages of the human malaria parasites and developing drugs against parasite liver stages.
AB - The two most prevalent human malaria parasites, Plasmodium falciparum and Plasmodium vivax, cause the majority of malaria-related morbidity and mortality. Compared with our knowledge about the erythrocytic stages, we understand little about the liver exoerythrocytic (EE) stages of the human malaria parasites. Our recent development of a hepatocyte line from normal human liver tissue is crucial for successful culturing of the liver stages of both P. falciparum and P. vivax. This technical advancement should be an important tool for directly studying developmental biology of the EE stages of the human malaria parasites and developing drugs against parasite liver stages.
UR - http://www.scopus.com/inward/record.url?scp=59249108734&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=59249108734&partnerID=8YFLogxK
U2 - 10.1007/978-1-59745-204-5_18
DO - 10.1007/978-1-59745-204-5_18
M3 - Article
C2 - 19089388
AN - SCOPUS:59249108734
SN - 1064-3745
VL - 470
SP - 263
EP - 273
JO - Methods in molecular biology (Clifton, N.J.)
JF - Methods in molecular biology (Clifton, N.J.)
ER -
