TY - JOUR
T1 - Current status of permanent total artificial hearts
AU - Davis, Paul K.
AU - Rosenberg, Gerson
AU - Snyder, Alan J.
AU - Pierce, William S.
N1 - Funding Information:
As of January 1, 1988, the National Heart, Lung, and Blood Institute of the National Institutes of Health began funding the development of these devices. The funding is in the form of contracts continuing through 1993. At that time, the devices should be ready to begin preclinical testing. Clinical application could begin by the year 2000.
PY - 1989/1
Y1 - 1989/1
N2 - Pneumatic total artificial hearts, although demonstrating utility as temporary mechanical circulatory support devices, have not demonstrated a great deal of promise as permanent cardiac replacements. The increasing number of patients who would be candidates for total heart replacement suggests a large role for a permanent implantable total artificial heart. To that end, the Pennsylvania State University is developing an electric motordriven total artificial heart; the results with implants in calves are encouraging. In this device, a roller-screw mechanism is used to translate the rotation of a brushless direct-current motor into rectilinear motion of a pusherplate assembly, which in turn empties the blood sacs. The total artificial heart of the future will function under automatic control without percutaneous leads, and this should provide the patient with a nearly normal lifestyle. Although further experimental efforts are necessary to prepare the device for clinical trials, the technology to provide a safe and reliable electric blood-pump system is at hand.
AB - Pneumatic total artificial hearts, although demonstrating utility as temporary mechanical circulatory support devices, have not demonstrated a great deal of promise as permanent cardiac replacements. The increasing number of patients who would be candidates for total heart replacement suggests a large role for a permanent implantable total artificial heart. To that end, the Pennsylvania State University is developing an electric motordriven total artificial heart; the results with implants in calves are encouraging. In this device, a roller-screw mechanism is used to translate the rotation of a brushless direct-current motor into rectilinear motion of a pusherplate assembly, which in turn empties the blood sacs. The total artificial heart of the future will function under automatic control without percutaneous leads, and this should provide the patient with a nearly normal lifestyle. Although further experimental efforts are necessary to prepare the device for clinical trials, the technology to provide a safe and reliable electric blood-pump system is at hand.
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U2 - 10.1016/0003-4975(89)90260-9
DO - 10.1016/0003-4975(89)90260-9
M3 - Article
C2 - 2912392
AN - SCOPUS:0024509453
SN - 0003-4975
VL - 47
SP - 172
EP - 178
JO - The Annals of thoracic surgery
JF - The Annals of thoracic surgery
IS - 1
ER -