Cystic fibrosis and hemolytic uremic syndrome coexisting during pregnancy

Lauren A. Plante, Esteban Ortega

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


BACKGROUND: As more women with cystic fibrosis are living into their reproductive years, this disease can complicate pregnancy and coexist with other entities. We report a case of cystic fibrosis with hemolytic uremic syndrome. CASE: An 18-year-old primigravida with cystic fibrosis was admitted at term with pulmonary symptoms, hypertension, and thrombocytopenia. She was delivered with the admitting diagnosis of severe preeclampsia. Postpartum, thrombocytopenia, and microangiopathic hemolytic anemia worsened. She developed renal failure and acute respiratory distress syndrome, requiring plasmapheresis, mechanical ventilation, and hemodialysis. Renal biopsy was consistent with the diagnosis of hemolytic uremic syndrome. CONCLUSION: Cystic fibrosis, a disease once managed predominantly by pediatric subspecialists, will be seen increasingly by physicians caring for adults, including obstetrician-gynecologists. We may also expect to see it coexisting with other disorders. The management of such patients may prove challenging.

Original languageEnglish (US)
Pages (from-to)930-932
Number of pages3
JournalObstetrics and gynecology
Issue number5 SUPPL. 1
StatePublished - 2002

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology


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