Cystic neuroendocrine tumor of the pancreas: A rare type of pancreatic cystic lesion accurately diagnosed and staged by EUS-FNA

Cystic neuroendocrine tumors of the pancreas are extremely rare. The tumors are solitary, solid or cystic and occur predominately in the pancreatic head. The exception is in the setting of MEN-1 (multiple endocrine neoplasia type 1) where multiple tumors occur. We present the case of a 42 year-old male with multiple cystic lesions of the pancreas, diagnosed as a cystic neuroendocrine tumor on endoscopic ultrasound fine needle biopsy, and the diffuse nature of involvement resulting in the first reported total pancreatectomy.