Cytomegalovirus colitis and viremia from mycophenolate mofetil monotherapy in birdshot chorioretinopathy

Seth M. Pantanelli; Yousuf M. Khalifa

doi:10.3109/09273948.2011.611961

Cytomegalovirus colitis and viremia from mycophenolate mofetil monotherapy in birdshot chorioretinopathy

Seth M. Pantanelli, Yousuf M. Khalifa

Department of Ophthalmology

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: To describe a case of cytomegalovirus (CMV) viremia and colitis in a patient on mycophenolate mofetil (MMF) monotherapy for birdshot chorioretinopathy. Design: Case report. Methods: Retrospective chart review. Results: Treatment with MMF 1.5g twice daily for 5 years led to leucopenia and a CD4 count of 299, which resulted in active CMV infection. Conclusions: Treatment with MMF alone may put otherwise immune-competent individuals at risk for opportunistic CMV infection. Greater awareness of this association may allow for better monitoring, earlier detection, and treatment of future cases.

Original language	English (US)
Pages (from-to)	450-452
Number of pages	3
Journal	Ocular Immunology and Inflammation
Volume	19
Issue number	6
DOIs	https://doi.org/10.3109/09273948.2011.611961
State	Published - Dec 2011

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Ophthalmology

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10.3109/09273948.2011.611961

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title = "Cytomegalovirus colitis and viremia from mycophenolate mofetil monotherapy in birdshot chorioretinopathy",

abstract = "Purpose: To describe a case of cytomegalovirus (CMV) viremia and colitis in a patient on mycophenolate mofetil (MMF) monotherapy for birdshot chorioretinopathy. Design: Case report. Methods: Retrospective chart review. Results: Treatment with MMF 1.5g twice daily for 5 years led to leucopenia and a CD4 count of 299, which resulted in active CMV infection. Conclusions: Treatment with MMF alone may put otherwise immune-competent individuals at risk for opportunistic CMV infection. Greater awareness of this association may allow for better monitoring, earlier detection, and treatment of future cases.",

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AB - Purpose: To describe a case of cytomegalovirus (CMV) viremia and colitis in a patient on mycophenolate mofetil (MMF) monotherapy for birdshot chorioretinopathy. Design: Case report. Methods: Retrospective chart review. Results: Treatment with MMF 1.5g twice daily for 5 years led to leucopenia and a CD4 count of 299, which resulted in active CMV infection. Conclusions: Treatment with MMF alone may put otherwise immune-competent individuals at risk for opportunistic CMV infection. Greater awareness of this association may allow for better monitoring, earlier detection, and treatment of future cases.

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Cytomegalovirus colitis and viremia from mycophenolate mofetil monotherapy in birdshot chorioretinopathy

Abstract

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