@article{e4392d02b39a4f93acdbbc792db8f662,
title = "Data descriptor: Dynamic contrastenhanced magnetic resonance imaging for head and neck cancers",
abstract = "Dynamic myraidpro contrast-enhanced magnetic resonance imaging (DCE-MRI) has been correlated with prognosis in head and neck squamous cell carcinoma as well as with changes in normal tissues. These studies implement different software, either commercial or in-house, and different scan protocols. Thus, the generalizability of the results is not confirmed. To assist in the standardization of quantitative metrics to confirm the generalizability of these previous studies, this data descriptor delineates in detail the DCE-MRI digital imaging and communications in medicine (DICOM) files with DICOM radiation therapy (RT) structure sets and digital reference objects (DROs), as well as, relevant clinical data that encompass a data set that can be used by all software for comparing quantitative metrics. Variable flip angle (VFA) with six flip angles and DCE-MRI scans with a temporal resolution of 5.5 s were acquired in the axial direction on a 3T MR scanner with a field of view of 25.6 cm, slice thickness of 4 mm, and 256×256 matrix size.",
author = "Hesham Elhalawani and Ger, {Rachel B.} and Mohamed, {Abdallah S.R.} and Awan, {Musaddiq J.} and Yao Ding and Kimberly Li and Fave, {Xenia J.} and Beers, {Andrew L.} and Brandon Driscoll and Hormuth, {David A.} and {Van Houdt}, {Petra J.} and Renjie He and Shouhao Zhou and Mathieu, {Kelsey B.} and Heng Li and Catherine Coolens and Caroline Chung and Bankson, {James A.} and Wei Huang and Jihong Wang and Sandulache, {Vlad C.} and Lai, {Stephen Y.} and Howell, {Rebecca M.} and Stafford, {R. Jason} and Yankeelov, {Thomas E.} and {Van Der Heide}, {Uulke A.} and Frank, {Steven J.} and Barboriak, {Daniel P.} and Hazle, {John D.} and Court, {Laurence E.} and Jayashree Kalpathy-Cramer and Fuller, {Clifton D.}",
note = "Funding Information: Multiple funders/agencies contributed to contributing personnel salary or project support during the study execution and manuscript preparation interval. Dr Elhalawani is supported in part by the philanthropic donations from the Family of Paul W. Beach to Dr G. Brandon Gunn. Mohamed and Fuller were supported via a National Science Foundation (NSF), Division of Mathematical Sciences, Joint NIH/NSF Initiative on Quantitative Approaches to Biomedical Big Data (QuBBD) Grant (NSF 1557679) and are currently supported by a NIH Big Data to Knowledge (BD2K) Program of the National Cancer Institute Early Stage Development of Technologies in Biomedical Computing, Informatics, and Big Data Science Award (1R01CA214825-01). Drs Lai, Mohamed and Fuller receive funding support from the National Institutes of Health (NIH)/National Institute for Dental and Craniofacial Research (NIDCR) (R01DE025248). This research is supported by the Andrew Sabin Family Foundation; Dr Fuller is a Sabin Family Foundation Fellow. Dr Fuller received/(s) grant and/or salary support from the NIH/NCI Head and Neck Specialized Programs of Research Excellence (SPORE) Developmental Research Program Career Development Award (P50CA097007-10); the NCI Paul Calabresi Clinical Oncology Program Award (K12 CA088084-06); a General Electric Healthcare/MD Anderson Center for Advanced Biomedical Imaging In-Kind Award; an Elekta AB/MD Anderson Department of Radiation Oncology Seed Grant; the Center for Radiation Oncology Research (CROR) at MD Anderson Cancer Center Seed Grant; the MD Anderson Institutional Research Grant (IRG) Program; and the NIH/NCI Cancer Center Support (Core) Grant CA016672 to The University of Texas MD Anderson Cancer Center (P30 CA016672). Rachel Ger is supported by the Rosalie B. Hite Graduate Fellowship in Cancer Research and the American Legion Auxiliary Fellowship in Cancer Research awarded by The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences. The research was accomplished under the auspices of infrastructure support provided by the multidisciplinary Steifel Oropharynx Research Program at the University of Texas MD Anderson Charles and Daneen Stiefel Center for Head and Neck Cancer. Dr Kalpathy-Cramer is supported by the National Cancer Institute (U24 CA180927-03, U01 CA154601-06). Drs Hormuth and Yankeelov are supported by the NIH (R01CA138599, U01CA174706) and Cancer Prevention Research Institute of Texas (CPRIT RR160005) Publisher Copyright: {\textcopyright} Author(s) 2018.",
year = "2018",
month = feb,
day = "13",
doi = "10.1038/sdata.2018.8",
language = "English (US)",
volume = "5",
journal = "Scientific Data",
issn = "2052-4463",
publisher = "Nature Publishing Group",
}