Abstract
Keeping a broad (RNA) perspective: Conventional biochemical detection systems only have a 100-fold linear response range. The range of potassium concentrations detected by an RNA G-quadruplex sequence can be broadened by intentionally populating multiple intermediate folding states (see scheme). The folding of the RNA G-quadruplexes was monitored by both circular dichroism and intrinsic fluorescence spectroscopy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 683-686 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 52 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 7 2013 |
All Science Journal Classification (ASJC) codes
- Catalysis
- General Chemistry
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