Deficiency of Wiskott–Aldrich syndrome protein has opposing effect on the pro-oncogenic pathway activation in nonmalignant versus malignant lymphocytes

Keyphrases

• Activator protein-1 (AP-1) 66%
• B Cells 33%
• B Lymphocytes 66%
• B-cell Malignancies 33%
• Cancer Risk 33%
• Cdc42 33%
• Cell Lineage 33%
• Cell Pair 33%
• DNA Binding 33%
• Downmodulation 33%
• ERK2 33%
• Hyperactivity 33%
• Immunodeficiency 33%
• Lymphocytes 100%
• Molecular Mechanism 33%
• NF-B 66%
• Non-associated 33%
• Nonmalignant 100%
• Oncogenesis 33%
• Oncogenic Pathways 100%
• Oncogenic Role 33%
• Oncogenic Signaling 33%
• Oncoprotein 33%
• Opposing Effects 100%
• Pairing Model 33%
• Pathway Activation 100%
• Primary Immunodeficiency 33%
• Pro-oncogenic 100%
• Protein Function 33%
• Protein S Deficiency 100%
• T Cells 100%
• Transcription Factor 33%
• Tumor Protein p53 (TP53) 33%
• Type-specific 33%
• X-linked Severe Combined Immunodeficiency 33%

Medicine and Dentistry

• B Cell 28%
• B Lymphocyte 28%
• Binding Affinity 14%
• Cancer 42%
• Cancer Risk 14%
• Carcinogenesis 14%
• Cell Lineage 14%
• Cell Signaling Pathway 14%
• DNA Binding 14%
• Hyperactivation 14%
• Immune Deficiency 28%
• Immunodeficiency 14%
• Mitogen Activated Protein Kinase 3 14%
• Oncoprotein 14%
• Protein Deficiency 42%
• Protein Function 14%
• T Cell 28%
• T Lymphocyte 28%
• Transcription Factors 14%
• Wiskott-Aldrich Syndrome 100%