Dehydration stress and Mayaro virus vector competence in Aedes aegypti

Jaime Manzano-Alvarez, Gerard Terradas, Christopher J. Holmes, Joshua B. Benoit, Jason L. Rasgon

Research output: Contribution to journalArticlepeer-review

Abstract

IMPORTANCE: Relative humidity (RH) is an environmental variable that affects mosquito physiology and can impact pathogen transmission. Low RH can induce dehydration in mosquitoes, leading to alterations in physiological and behavioral responses such as blood-feeding and host-seeking behavior. We evaluated the effects of a temporal drop in RH (RH shock) on mortality and Mayaro virus vector competence in Ae. aegypti. While dehydration induced by humidity shock did not impact virus infection, we detected a significant effect of dehydration on mosquito mortality and blood-feeding frequency, which could significantly impact transmission dynamics.

Original languageEnglish (US)
Pages (from-to)e0069523
JournalJournal of virology
Volume97
Issue number12
DOIs
StatePublished - Dec 21 2023

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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