Dehydration stress and Mayaro virus vector competence in Aedes aegypti

Jaime Manzano-Alvarez; Gerard Terradas; Christopher J. Holmes; Joshua B. Benoit; Jason L. Rasgon

doi:10.1128/jvi.00695-23

Dehydration stress and Mayaro virus vector competence in Aedes aegypti

Jaime Manzano-Alvarez, Gerard Terradas, Christopher J. Holmes, Joshua B. Benoit, Jason L. Rasgon

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

IMPORTANCE: Relative humidity (RH) is an environmental variable that affects mosquito physiology and can impact pathogen transmission. Low RH can induce dehydration in mosquitoes, leading to alterations in physiological and behavioral responses such as blood-feeding and host-seeking behavior. We evaluated the effects of a temporal drop in RH (RH shock) on mortality and Mayaro virus vector competence in Ae. aegypti. While dehydration induced by humidity shock did not impact virus infection, we detected a significant effect of dehydration on mosquito mortality and blood-feeding frequency, which could significantly impact transmission dynamics.

Original language	English (US)
Pages (from-to)	e0069523
Journal	Journal of virology
Volume	97
Issue number	12
DOIs	https://doi.org/10.1128/jvi.00695-23
State	Published - Dec 21 2023

All Science Journal Classification (ASJC) codes

Microbiology
Immunology
Insect Science
Virology

Access to Document

10.1128/jvi.00695-23

Cite this

@article{e679eed8e0e14257af05e984b71fb8a2,

title = "Dehydration stress and Mayaro virus vector competence in Aedes aegypti",

abstract = "IMPORTANCE: Relative humidity (RH) is an environmental variable that affects mosquito physiology and can impact pathogen transmission. Low RH can induce dehydration in mosquitoes, leading to alterations in physiological and behavioral responses such as blood-feeding and host-seeking behavior. We evaluated the effects of a temporal drop in RH (RH shock) on mortality and Mayaro virus vector competence in Ae. aegypti. While dehydration induced by humidity shock did not impact virus infection, we detected a significant effect of dehydration on mosquito mortality and blood-feeding frequency, which could significantly impact transmission dynamics.",

author = "Jaime Manzano-Alvarez and Gerard Terradas and Holmes, {Christopher J.} and Benoit, {Joshua B.} and Rasgon, {Jason L.}",

year = "2023",

month = dec,

day = "21",

doi = "10.1128/jvi.00695-23",

language = "English (US)",

volume = "97",

pages = "e0069523",

journal = "Journal of virology",

issn = "0022-538X",

publisher = "American Society for Microbiology",

number = "12",

}

TY - JOUR

T1 - Dehydration stress and Mayaro virus vector competence in Aedes aegypti

AU - Manzano-Alvarez, Jaime

AU - Terradas, Gerard

AU - Holmes, Christopher J.

AU - Benoit, Joshua B.

AU - Rasgon, Jason L.

PY - 2023/12/21

Y1 - 2023/12/21

N2 - IMPORTANCE: Relative humidity (RH) is an environmental variable that affects mosquito physiology and can impact pathogen transmission. Low RH can induce dehydration in mosquitoes, leading to alterations in physiological and behavioral responses such as blood-feeding and host-seeking behavior. We evaluated the effects of a temporal drop in RH (RH shock) on mortality and Mayaro virus vector competence in Ae. aegypti. While dehydration induced by humidity shock did not impact virus infection, we detected a significant effect of dehydration on mosquito mortality and blood-feeding frequency, which could significantly impact transmission dynamics.

AB - IMPORTANCE: Relative humidity (RH) is an environmental variable that affects mosquito physiology and can impact pathogen transmission. Low RH can induce dehydration in mosquitoes, leading to alterations in physiological and behavioral responses such as blood-feeding and host-seeking behavior. We evaluated the effects of a temporal drop in RH (RH shock) on mortality and Mayaro virus vector competence in Ae. aegypti. While dehydration induced by humidity shock did not impact virus infection, we detected a significant effect of dehydration on mosquito mortality and blood-feeding frequency, which could significantly impact transmission dynamics.

UR - http://www.scopus.com/inward/record.url?scp=85180536517&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85180536517&partnerID=8YFLogxK

U2 - 10.1128/jvi.00695-23

DO - 10.1128/jvi.00695-23

M3 - Article

C2 - 38051046

AN - SCOPUS:85180536517

SN - 0022-538X

VL - 97

SP - e0069523

JO - Journal of virology

JF - Journal of virology

IS - 12

ER -

Dehydration stress and Mayaro virus vector competence in Aedes aegypti

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this