TY - JOUR
T1 - Delayed-onset, bleb-associated endophthalmitis caused by Lecythophora mutabilis
AU - Scott, Ingrid U.
AU - Cruz-Villegas, Vanessa
AU - Flynn, Harry W.
AU - Miller, Darlene
N1 - Funding Information:
Supported in part by Research to Prevent Blindness, Inc., New York, New York.
PY - 2004/3
Y1 - 2004/3
N2 - Purpose To report delayed-onset, bleb-associated endophthalmitis caused by Lecythophora mutabilis. Design Interventional case report. Methods Description of an otherwise healthy woman who developed delayed-onset fungal endophthalmitis associated with a preexisting filtering bleb. Results A 57-year-old woman who underwent trabeculectomy with Mitomycin C in her left eye 8 years earlier presented with a 10-day history of pain and decreased vision in her left eye. She underwent anterior chamber and vitreous taps and injection of intraocular antibiotics. Cultures grew the mold Lecythophora mutabilis. The patient underwent treatment with intraocular and systemic antifungal agents, three pars plana vitrectomies, partial iridectomy, and cryopexy to the bleb and angle structures. Four months after her last treatment, her left eye shows no residual infection, and vision corrects to 20/80. Conclusion Bleb-associated endophthalmitis caused by L. mutabilis is resistant to amphotericin B but responsive to intravitreal and systemic voriconazole together with pars plana vitrectomy, iridectomy, and cryopexy to the bleb and angle structures.
AB - Purpose To report delayed-onset, bleb-associated endophthalmitis caused by Lecythophora mutabilis. Design Interventional case report. Methods Description of an otherwise healthy woman who developed delayed-onset fungal endophthalmitis associated with a preexisting filtering bleb. Results A 57-year-old woman who underwent trabeculectomy with Mitomycin C in her left eye 8 years earlier presented with a 10-day history of pain and decreased vision in her left eye. She underwent anterior chamber and vitreous taps and injection of intraocular antibiotics. Cultures grew the mold Lecythophora mutabilis. The patient underwent treatment with intraocular and systemic antifungal agents, three pars plana vitrectomies, partial iridectomy, and cryopexy to the bleb and angle structures. Four months after her last treatment, her left eye shows no residual infection, and vision corrects to 20/80. Conclusion Bleb-associated endophthalmitis caused by L. mutabilis is resistant to amphotericin B but responsive to intravitreal and systemic voriconazole together with pars plana vitrectomy, iridectomy, and cryopexy to the bleb and angle structures.
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U2 - 10.1016/j.ajo.2003.08.037
DO - 10.1016/j.ajo.2003.08.037
M3 - Article
C2 - 15013895
AN - SCOPUS:1542267388
SN - 0002-9394
VL - 137
SP - 583
EP - 585
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 3
ER -