Delayed rupture of the spleen and streptokinase therapy

Robert Nam, Michele M. Carr, Christopher G. Jamieson

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Delayed rupture of the spleen is a rare but serious complication of blunt abdominal trauma. A 47-year-old woman with a history of fractured pelvis from a motor vehicle accident 6 months earlier presented with evidence of a myocardial infarction. Subsequent streptokinase administration was complicated by splenic rupture, which was managed by evacuation of the clotted blood and splenectomy. The patient made a complete recovery. The risk of splenic rupture and bleeding complications resulting from thrombolytic therapy for myocardial infarction is discussed, as are the controversy over whether delayed splenic rupture is a true diagnosis, the mechanism of rupture and the clues to impending rupture.

Original languageEnglish (US)
Pages (from-to)151-154
Number of pages4
JournalCanadian Journal of Surgery
Issue number2
StatePublished - Apr 1996

All Science Journal Classification (ASJC) codes

  • Surgery


Dive into the research topics of 'Delayed rupture of the spleen and streptokinase therapy'. Together they form a unique fingerprint.

Cite this