Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects

Neuroscience

• Pervasive Developmental Disorder 100%
• Interneuron 100%
• Autism 100%
• Wnt Signaling Pathway 66%
• Parvalbumin 66%
• Behavior (Neuroscience) 33%
• Nerve Cell Differentiation 33%
• Amygdala 33%
• Neuronal Activity 33%
• Catenin 33%
• Social Interaction 33%
• C-Fos 33%
• Dentate Gyrus 33%
• Loss of Function Mutation 33%
• Mental Disorder 33%
• Compulsive Behavior 33%
• Spatial Memory 33%

Keyphrases

• Autism 100%
• Inhibitory Neurons 100%
• CTNNB1 100%
• Behavioral Defects 100%
• Autism Spectrum Disorder 30%
• Knock-in Mouse Model 20%
• Parvalbumin Interneurons 20%
• In Cancer 10%
• Spatial Memory 10%
• Mental Disorders 10%
• Neuronal Subtypes 10%
• Intellectual Disability 10%
• Rare mutation 10%
• Motor Function 10%
• Social Interaction 10%
• Neurodevelopment 10%
• Cortex 10%
• C-Fos 10%
• Neuronal Activity 10%
• Gain-of-function mutation 10%
• Type-specific 10%
• Catenin 10%
• Object Recognition 10%
• Wnt Signaling Pathway 10%
• Dentate Gyrus 10%
• Conditional Knockout 10%
• Amygdala 10%
• Repetitive Behavior 10%
• Autistic Traits 10%
• Canonical Wnt Pathway 10%