TY - JOUR
T1 - Deprescribing strategies in older patients with heart failure
AU - Tersalvi, Gregorio
AU - Beltrani, Vittorio
AU - Peronti, Marco
AU - Furlan, Ludovico
AU - Foy, Andrew
AU - Biasco, Luigi
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Società Italiana di Medicina Interna (SIMI) 2024.
PY - 2025/3
Y1 - 2025/3
N2 - Older patients with heart failure are particularly vulnerable due to a wide range of associated comorbidities, disability, and frailty. This population often receives multiple prescriptions, increasing the risk of adverse drug reactions, non-adherence, and drug interactions. Deprescribing, which involves reducing the number of medications to the lowest clinically reasonable limit, has the potential to decrease the risk of drug interactions and enhance patients’ quality of life. Moreover, simplifying medication regimens may improve adherence to essential heart failure therapies. This scientific review aims to comprehensively examine deprescribing strategies in older patients with heart failure. It explores the rationale, challenges, benefits, and potential approaches to optimizing medication regimens in this vulnerable population. Furthermore, the review suggests a practical, step-by-step approach for performing deprescribing in older patients with heart failure.
AB - Older patients with heart failure are particularly vulnerable due to a wide range of associated comorbidities, disability, and frailty. This population often receives multiple prescriptions, increasing the risk of adverse drug reactions, non-adherence, and drug interactions. Deprescribing, which involves reducing the number of medications to the lowest clinically reasonable limit, has the potential to decrease the risk of drug interactions and enhance patients’ quality of life. Moreover, simplifying medication regimens may improve adherence to essential heart failure therapies. This scientific review aims to comprehensively examine deprescribing strategies in older patients with heart failure. It explores the rationale, challenges, benefits, and potential approaches to optimizing medication regimens in this vulnerable population. Furthermore, the review suggests a practical, step-by-step approach for performing deprescribing in older patients with heart failure.
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U2 - 10.1007/s11739-024-03791-5
DO - 10.1007/s11739-024-03791-5
M3 - Review article
C2 - 39406965
AN - SCOPUS:105001473081
SN - 1828-0447
VL - 20
SP - 599
EP - 609
JO - Internal and Emergency Medicine
JF - Internal and Emergency Medicine
IS - 2
M1 - e008251
ER -