Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction

Hemakesh Mohapatra; Kyle M. Schmid; Scott T. Phillips

doi:10.1039/c2cc17566e

Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction

Hemakesh Mohapatra
, Kyle M. Schmid
, Scott T. Phillips

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

This Communication describes three small molecule reagents that amplify the signal for a detection event via an autocatalytic reaction. Two signals are obtained from each reagent: (i) the dibenzofulvene chromophore and (ii) piperidine, which can be visualized using a pH indicator dye. The reagents are demonstrated in a model assay for palladium.

Original language	English (US)
Pages (from-to)	3018-3020
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	24
DOIs	https://doi.org/10.1039/c2cc17566e
State	Published - Feb 22 2012

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c2cc17566e

Cite this

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title = "Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction",

abstract = "This Communication describes three small molecule reagents that amplify the signal for a detection event via an autocatalytic reaction. Two signals are obtained from each reagent: (i) the dibenzofulvene chromophore and (ii) piperidine, which can be visualized using a pH indicator dye. The reagents are demonstrated in a model assay for palladium.",

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AU - Mohapatra, Hemakesh

AU - Schmid, Kyle M.

AU - Phillips, Scott T.

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Y1 - 2012/2/22

N2 - This Communication describes three small molecule reagents that amplify the signal for a detection event via an autocatalytic reaction. Two signals are obtained from each reagent: (i) the dibenzofulvene chromophore and (ii) piperidine, which can be visualized using a pH indicator dye. The reagents are demonstrated in a model assay for palladium.

AB - This Communication describes three small molecule reagents that amplify the signal for a detection event via an autocatalytic reaction. Two signals are obtained from each reagent: (i) the dibenzofulvene chromophore and (ii) piperidine, which can be visualized using a pH indicator dye. The reagents are demonstrated in a model assay for palladium.

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UR - https://www.scopus.com/pages/publications/84857590761#tab=citedBy

U2 - 10.1039/c2cc17566e

DO - 10.1039/c2cc17566e

M3 - Article

C2 - 22327299

AN - SCOPUS:84857590761

SN - 1359-7345

VL - 48

SP - 3018

EP - 3020

JO - Chemical Communications

JF - Chemical Communications

IS - 24

ER -

Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction

Abstract

All Science Journal Classification (ASJC) codes

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