Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors

  • Dale L. Boger
  • , Monica J. Kochanny
  • , Hui Cai
  • , Diane Wyatt
  • , Paul A. Kitos
  • , M. S. Warren
  • , J. Ramcharan
  • , Lata T. Gooljarsingh
  • , Stephen J. Benkovic

Research output: Contribution to journalArticlepeer-review

Abstract

The synthesis and evaluation of 1 4 as potential inhibitors of GAR Tfase and AICAR Tfase are detailed. Copyright (C) 1998 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)643-659
Number of pages17
JournalBioorganic and Medicinal Chemistry
Volume6
Issue number6
DOIs
StatePublished - Jun 1998

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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