Determination of polycyclic aromatic hydrocarbons in urine by solid phase extraction and GC/HRMS

Wenlin Huang; Christopher J. Smith; Charisse J. Walcott; Zheng Li; Selvin Edwards; Melvin Bullock; James Grainger; Donald George Jr Patterson

Determination of polycyclic aromatic hydrocarbons in urine by solid phase extraction and GC/HRMS

Wenlin Huang, Christopher J. Smith, Charisse J. Walcott, Zheng Li, Selvin Edwards, Melvin Bullock, James Grainger, Donald George Jr Patterson

Forensic Science Program

Research output: Contribution to conference › Paper › peer-review

Abstract

The polycyclic aromatic hydrocarbons (PAH) in urine were analyzed using analytic method of solid phase extraction (SPE). The urine samples were spiked with 9 carbon-13 labeled standards which were hydrolyzed by β- glucuronidase/arylsulfatase. The solutions were blown in an evaporator and extracts were reconstituted in toluene. The method detection limits (MDL) ranged from 2 ng/L for 1-hydroxypyrene to 43.5 ng/L for 1-hydroxynaphthalene which produced good specificity, precision, linearity and recovery.

Original language	English (US)
Pages	683-684
Number of pages	2
State	Published - Dec 1 2002
Event	Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States Duration: Jun 2 2002 → Jun 6 2002

Other

Other	Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
Country/Territory	United States
City	Orlando, FL
Period	6/2/02 → 6/6/02

All Science Journal Classification (ASJC) codes

Spectroscopy

Cite this

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title = "Determination of polycyclic aromatic hydrocarbons in urine by solid phase extraction and GC/HRMS",

abstract = "The polycyclic aromatic hydrocarbons (PAH) in urine were analyzed using analytic method of solid phase extraction (SPE). The urine samples were spiked with 9 carbon-13 labeled standards which were hydrolyzed by β- glucuronidase/arylsulfatase. The solutions were blown in an evaporator and extracts were reconstituted in toluene. The method detection limits (MDL) ranged from 2 ng/L for 1-hydroxypyrene to 43.5 ng/L for 1-hydroxynaphthalene which produced good specificity, precision, linearity and recovery.",

author = "Wenlin Huang and Smith, {Christopher J.} and Walcott, {Charisse J.} and Zheng Li and Selvin Edwards and Melvin Bullock and James Grainger and Patterson, {Donald George Jr}",

year = "2002",

month = dec,

day = "1",

language = "English (US)",

pages = "683--684",

note = "Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics ; Conference date: 02-06-2002 Through 06-06-2002",

}

Determination of polycyclic aromatic hydrocarbons in urine by solid phase extraction and GC/HRMS. / Huang, Wenlin; Smith, Christopher J.; Walcott, Charisse J. et al.
2002. 683-684 Paper presented at Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, United States.

Research output: Contribution to conference › Paper › peer-review

TY - CONF

T1 - Determination of polycyclic aromatic hydrocarbons in urine by solid phase extraction and GC/HRMS

AU - Huang, Wenlin

AU - Smith, Christopher J.

AU - Walcott, Charisse J.

AU - Li, Zheng

AU - Edwards, Selvin

AU - Bullock, Melvin

AU - Grainger, James

AU - Patterson, Donald George Jr

PY - 2002/12/1

Y1 - 2002/12/1

N2 - The polycyclic aromatic hydrocarbons (PAH) in urine were analyzed using analytic method of solid phase extraction (SPE). The urine samples were spiked with 9 carbon-13 labeled standards which were hydrolyzed by β- glucuronidase/arylsulfatase. The solutions were blown in an evaporator and extracts were reconstituted in toluene. The method detection limits (MDL) ranged from 2 ng/L for 1-hydroxypyrene to 43.5 ng/L for 1-hydroxynaphthalene which produced good specificity, precision, linearity and recovery.

AB - The polycyclic aromatic hydrocarbons (PAH) in urine were analyzed using analytic method of solid phase extraction (SPE). The urine samples were spiked with 9 carbon-13 labeled standards which were hydrolyzed by β- glucuronidase/arylsulfatase. The solutions were blown in an evaporator and extracts were reconstituted in toluene. The method detection limits (MDL) ranged from 2 ng/L for 1-hydroxypyrene to 43.5 ng/L for 1-hydroxynaphthalene which produced good specificity, precision, linearity and recovery.

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M3 - Paper

AN - SCOPUS:2442659476

SP - 683

EP - 684

T2 - Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics

Y2 - 2 June 2002 through 6 June 2002

ER -

Determination of polycyclic aromatic hydrocarbons in urine by solid phase extraction and GC/HRMS

Abstract

Other

All Science Journal Classification (ASJC) codes

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