@article{ea8519346ff1409fb11a69d508a00fa6,
title = "Development and expansion of high-quality control region databases to improve forensic mtDNA evidence interpretation",
abstract = "In an effort to increase the quantity, breadth and availability of mtDNA databases suitable for forensic comparisons, we have developed a high-throughput process to generate approximately 5000 control region sequences per year from regional US populations, global populations from which the current US population is derived and global populations currently under-represented in available forensic databases. The system utilizes robotic instrumentation for all laboratory steps from pre-extraction through sequence detection, and a rigorous eight-step, multi-laboratory data review process with entirely electronic data transfer. Over the past 3 years, nearly 10,000 control region sequences have been generated using this approach. These data are being made publicly available and should further address the need for consistent, high-quality mtDNA databases for forensic testing.",
author = "Irwin, {Jodi A.} and Saunier, {Jessica L.} and Strouss, {Katharine M.} and Sturk, {Kimberly A.} and Diegoli, {Toni M.} and Just, {Rebecca S.} and Coble, {Michael D.} and Walther Parson and Parsons, {Thomas J.}",
note = "Funding Information: The authors wish to thank Jennifer O{\textquoteright}Callaghan, Carla Paintner, Kimberly Watson, Heather Williams, Melissa Scheible, Leslie Mounkes, and Naila Bahtri (AFDIL) for data generation, as well as Anita Brandst{\"a}tter (EMPOP, Innsbruck Medical University, Austria) for assistance with database confirmation. We also thank James Canik, Kevin Carroll, Brion Smith, Louis Finelli and James Ross (AFDIL) for logistical, administrative, and computer support. A large portion of this work was funded by United States National Institute of Justice grants 2000-IJ-CX-K010 and 2003-DN-R-086 to TJP, as well as an inter-agency agreement 2005-91821-DC-IJ with the Armed Forces Institute of Pathology. The opinions and assertions contained herein are solely those of the authors and are not to be construed as official or as views of the U.S. Department of Defense, or the U.S. Department of the Army. Copyright: Copyright 2009 Elsevier B.V., All rights reserved.",
year = "2007",
month = jun,
doi = "10.1016/j.fsigen.2007.01.019",
language = "English (US)",
volume = "1",
pages = "154--157",
journal = "Forensic Science International: Genetics",
issn = "1872-4973",
publisher = "Elsevier Ireland Ltd",
number = "2",
}