@article{1f37d95c49ca4d5dbfafc774f1aba79a,
title = "Development and validation of a model for estimating premorbid verbal intelligence in the elderly",
abstract = "In a preliminary effort to improve the early diagnosis of dementia, we developed a regression-based method for estimating premorbid intelligence measured by the ability to read irregular words from the American version of the Nelson Adult Reading Test (AMNART). Using errors on the AMNART and years of education, a model for predicting current verbal intelligence (VIQ) was developed in a sample of nondemented elderly. Double cross validation showed that the model had high accuracy and stability in estimating current VIQ in nondemented subjects. The model was then used to estimate premorbid VIQ in mildly demented subjects. Estimated premorbid IQ exceeded current IQ by at least 10 points and did not differ from that of nondemented subjects. Less than 10% of nondemented elderly had discrepancies that were as large. If intellectual decline predicts future functional loss and can be reliably measured using cross-sectional data, the requirement of functional impairment may be an unnecessary barrier to the early diagnosis of dementia.",
author = "E. Grober and M. Sliwinski",
note = "Funding Information: The main purpose of this study was to develop a robust method for estimating premorbid intelligence in the elderly. The discrepency between premorbid and current intelligence provides an index of intellectual decline which is a core * This research was supported by US. Public Health Service Grant AGO-3949 and was presented, in part, at the 18th Annual Meeting of the International Neuropsychological Society, February, 1990. From the Saul R. Korey Department of Neurology and the Rose F. Kennedy Center for Mental Retardation and Human Development, Albert Einstein College of Medicine, Bronx, NY. Supported by USPHS grants AG 03949. The authors thank the participants of the Teaching Nursing Home Projects for making this study possible, David Scarisbrick for programming, Shereen Bang, Rochelle Ausubel, and Heather Gitlin for testing subjects, Richard Lipton for extended discussions on the topic, and Herman Buschke, Robert Golden, and Jonathan Tobin for their valuable comments. Address correspondence to: Ellen Grober, Ph.D., Department of Neurology, Albert Einstein College of Medicine, Van Etten Hospital, Rm. 319, 1300 Morris Park Ave, Bronx, NY 10461, USA Accepted for publication: February 9, 1991.",
year = "1991",
doi = "10.1080/01688639108405109",
language = "English (US)",
volume = "13",
pages = "933--949",
journal = "Journal of Clinical and Experimental Neuropsychology",
issn = "0168-8634",
publisher = "Psychology Press Ltd",
number = "6",
}