Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation

Basma Hashmi; Lauren D. Zarzar; Tadanori Mammoto; Akiko Mammoto; Amanda Jiang; Joanna Aizenberg; Donald E. Ingber

doi:10.1002/adma.201304995

Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation

Basma Hashmi
, Lauren D. Zarzar
, Tadanori Mammoto
, Akiko Mammoto
, Amanda Jiang
, Joanna Aizenberg
, Donald E. Ingber

Chemistry

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

A biologically inspired thermoresponsive polymer has been developed that mechanically induces tooth differentiation in vitro and in vivo by promoting mesenchymal cell compaction as seen in each pore of the scaffold. This normally occurs during the physiological mesenchymal condensation response that triggers tooth formation in the embryo.

Original language	English (US)
Pages (from-to)	3253-3257
Number of pages	5
Journal	Advanced Materials
Volume	26
Issue number	20
DOIs	https://doi.org/10.1002/adma.201304995
State	Published - May 28 2014

All Science Journal Classification (ASJC) codes

General Materials Science
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201304995

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title = "Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation",

abstract = "A biologically inspired thermoresponsive polymer has been developed that mechanically induces tooth differentiation in vitro and in vivo by promoting mesenchymal cell compaction as seen in each pore of the scaffold. This normally occurs during the physiological mesenchymal condensation response that triggers tooth formation in the embryo.",

author = "Basma Hashmi and Zarzar, \{Lauren D.\} and Tadanori Mammoto and Akiko Mammoto and Amanda Jiang and Joanna Aizenberg and Ingber, \{Donald E.\}",

year = "2014",

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doi = "10.1002/adma.201304995",

language = "English (US)",

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journal = "Advanced Materials",

issn = "0935-9648",

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T1 - Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation

AU - Hashmi, Basma

AU - Zarzar, Lauren D.

AU - Mammoto, Tadanori

AU - Mammoto, Akiko

AU - Jiang, Amanda

AU - Aizenberg, Joanna

AU - Ingber, Donald E.

PY - 2014/5/28

Y1 - 2014/5/28

N2 - A biologically inspired thermoresponsive polymer has been developed that mechanically induces tooth differentiation in vitro and in vivo by promoting mesenchymal cell compaction as seen in each pore of the scaffold. This normally occurs during the physiological mesenchymal condensation response that triggers tooth formation in the embryo.

AB - A biologically inspired thermoresponsive polymer has been developed that mechanically induces tooth differentiation in vitro and in vivo by promoting mesenchymal cell compaction as seen in each pore of the scaffold. This normally occurs during the physiological mesenchymal condensation response that triggers tooth formation in the embryo.

UR - https://www.scopus.com/pages/publications/84901485098

UR - https://www.scopus.com/pages/publications/84901485098#tab=citedBy

U2 - 10.1002/adma.201304995

DO - 10.1002/adma.201304995

M3 - Article

C2 - 24550068

AN - SCOPUS:84901485098

SN - 0935-9648

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SP - 3253

EP - 3257

JO - Advanced Materials

JF - Advanced Materials

IS - 20

ER -

Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation

Abstract

All Science Journal Classification (ASJC) codes

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