TY - JOUR
T1 - Dexmedetomidine as an Adjunct for Regional Anesthetic Nerve Blocks
AU - Rao, Srikantha
AU - Rajan, Niraja
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.
PY - 2021/2
Y1 - 2021/2
N2 - Purpose of Review: This article will review current evidence related to the use of dexmedetomidine as an adjuvant for regional anesthesia. Recent Findings: Adjuvants, frequently used during regional anesthesia, act synergistically with local anesthetics thus enhancing the quality of regional anesthesia while minimizing adverse effects. These adjuvants may be administered via different routes including topical, perineural, neuraxial, and systemic. Summary: Recent studies indicate that dexmedetomidine prolongs the duration of intravenous regional anesthesia, peripheral nerve blocks, and spinal analgesia. Controversy regarding potential neurotoxicity of perineural dexmedetomidine in patients with diabetic neuropathy requires further evaluation.
AB - Purpose of Review: This article will review current evidence related to the use of dexmedetomidine as an adjuvant for regional anesthesia. Recent Findings: Adjuvants, frequently used during regional anesthesia, act synergistically with local anesthetics thus enhancing the quality of regional anesthesia while minimizing adverse effects. These adjuvants may be administered via different routes including topical, perineural, neuraxial, and systemic. Summary: Recent studies indicate that dexmedetomidine prolongs the duration of intravenous regional anesthesia, peripheral nerve blocks, and spinal analgesia. Controversy regarding potential neurotoxicity of perineural dexmedetomidine in patients with diabetic neuropathy requires further evaluation.
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U2 - 10.1007/s11916-020-00926-z
DO - 10.1007/s11916-020-00926-z
M3 - Review article
C2 - 33533982
AN - SCOPUS:85100371459
SN - 1531-3433
VL - 25
JO - Current Pain and Headache Reports
JF - Current Pain and Headache Reports
IS - 2
M1 - 8
ER -