Dexmedetomidine as an Adjunct for Regional Anesthetic Nerve Blocks

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13 Scopus citations


Purpose of Review: This article will review current evidence related to the use of dexmedetomidine as an adjuvant for regional anesthesia. Recent Findings: Adjuvants, frequently used during regional anesthesia, act synergistically with local anesthetics thus enhancing the quality of regional anesthesia while minimizing adverse effects. These adjuvants may be administered via different routes including topical, perineural, neuraxial, and systemic. Summary: Recent studies indicate that dexmedetomidine prolongs the duration of intravenous regional anesthesia, peripheral nerve blocks, and spinal analgesia. Controversy regarding potential neurotoxicity of perineural dexmedetomidine in patients with diabetic neuropathy requires further evaluation.

Original languageEnglish (US)
Article number8
JournalCurrent Pain and Headache Reports
Issue number2
StatePublished - Feb 2021

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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