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DFMO inhibition of neuroblastoma tumorigenesis
Divya Gandra
, David H. Mulama
, David M. Foureau
, Kimberly Q. McKinney
, Elizabeth Kim
, Kaitlyn Smith
, Jason Haw
, Abhinav Nagulapally
,
Giselle L. Saulnier Sholler
Department of Pediatrics
Division of Hematology and Oncology
Penn State Neuroscience Institute
Department of Neuroscience and Experimental Therapeutics
Research output
:
Contribution to journal
›
Article
›
peer-review
13
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Scopus citations
Overview
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Immunology and Microbiology
Cell Viability
100%
Cell Line
50%
IC50
50%
Cytotoxicity
50%
Dilution
50%
Cell Cycle
50%
Overall Survival
50%
Protein Expression
50%
Murine
50%
Xenograft
50%
Neuroblastoma Cell Line
50%
Cell Cycle Checkpoint
50%
Programmed Cell Death
50%
Event Free Survival
50%
Keyphrases
Tumorigenesis
100%
Neuroblastoma
100%
Difluoromethylornithine
100%
Clinically Significant
22%
Cell Viability
22%
Tumor Formation
22%
Cellular Process
22%
Dose-dependent
22%
Statistical Analysis
11%
Maintenance Therapy
11%
Tumor Progression
11%
Chlorophyll a (Chl a)
11%
In Vitro Assay
11%
Overall Survival
11%
Protein Expression
11%
Apoptosis
11%
Neuroblastoma Cell Line
11%
Cytotoxicity
11%
Significant Loss
11%
Murine Model
11%
Inhibit Tumor
11%
IC50 Value
11%
Event-free Survival
11%
Physiologically Relevant
11%
Xenograft
11%
Limiting Dilution
11%
Apoptotic Activity
11%
Cytostatic
11%
Neurospheres
11%
Tumor Initiation
11%
Mechanistic Studies
11%
β-galactosidase Activity
11%
High-risk Neuroblastoma
11%
S Phase Cell Cycle Arrest
11%
Viability Cell
11%
Therapeutic Dose
11%
Medicine and Dentistry
Carcinogenesis
100%
Ganglioneuroblastoma
100%
Eflornithine
100%
Cell Viability
22%
Cell Line
11%
Maintenance Therapy
11%
Tumor Progression
11%
IC50
11%
Overall Survival
11%
Protein Expression
11%
Cell Cycle
11%
Neuroblastoma Cell Line
11%
Cell Cycle Arrest
11%
Event Free Survival
11%
Cytotoxicity
11%
S Phase
11%
Xenograft
11%
Cell Cycle Checkpoint
11%
Tumor Initiation
11%
Diseases
11%
Cytostatic
11%
Neuroscience
Neuroblastoma
100%
Carcinogenesis
100%
Eflornithine
100%
Cell Line
22%
Neurosphere
22%
Cell Viability
22%
Cellular Processes
22%
Protein Expression
11%
Cell Cycle
11%
Cytotoxicity
11%
Cell Cycle Checkpoint
11%
Programmed Cell Death
11%
Biochemistry, Genetics and Molecular Biology
Carcinogenesis
100%
Cell Viability
40%
Protein Expression
20%
IC50
20%
Cell Cycle
20%
Tumor Progression
20%
Cell Cycle Arrest
20%
S Phase
20%
Overall Survival
20%
Event Free Survival
20%
Dilution
20%
Cytotoxicity
20%
Murine
20%
Cell Cycle Checkpoint
20%
Beta-Galactosidase
20%
Tumor Initiation
20%
Programmed Cell Death
20%
Pharmacology, Toxicology and Pharmaceutical Science
Carcinogenesis
100%
Neuroblastoma
100%
Eflornithine
100%
Cell Viability
22%
Cellular Processes
22%
Neoplasm
11%
IC50
11%
Overall Survival
11%
Event Free Survival
11%
Murine
11%
Cytotoxicity
11%
Diseases
11%
Cytostatic
11%