TY - JOUR
T1 - Diagnosis and Treatment of Fat Embolism
AU - Evarts, Charles M.
PY - 1965/11/22
Y1 - 1965/11/22
N2 - The occurrence of fat embolism as a complication of skeletal trauma has been of interest for more than a century. The controversy in regard to the source of the embolic fat has still not been resolved. The incidence of fat embolism is relatively high both on the battlefield and in civilian life (Table 1).1-7 The severity of this complication in association with multiple injuries, especially with fractures of long bones, is not generally appreciated. Systemic fat embolism produces a clinical syndrome with characteristic findings and pertinent laboratory results. With a better understanding of the underlying pathophysiological mechanisms, treatment has become more specific and less empirical. Pathogenesis The pathogenesis of fat embolism is still subject to conjecture and controversy. The genesis of the embolic fat is postulated as being either mechanical or physiochemical. Although it is possible that intravasation of fat into vascular channels can occur after trauma, recent studies8.
AB - The occurrence of fat embolism as a complication of skeletal trauma has been of interest for more than a century. The controversy in regard to the source of the embolic fat has still not been resolved. The incidence of fat embolism is relatively high both on the battlefield and in civilian life (Table 1).1-7 The severity of this complication in association with multiple injuries, especially with fractures of long bones, is not generally appreciated. Systemic fat embolism produces a clinical syndrome with characteristic findings and pertinent laboratory results. With a better understanding of the underlying pathophysiological mechanisms, treatment has become more specific and less empirical. Pathogenesis The pathogenesis of fat embolism is still subject to conjecture and controversy. The genesis of the embolic fat is postulated as being either mechanical or physiochemical. Although it is possible that intravasation of fat into vascular channels can occur after trauma, recent studies8.
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U2 - 10.1001/jama.1965.03090210063016
DO - 10.1001/jama.1965.03090210063016
M3 - Article
C2 - 5898073
AN - SCOPUS:0013852756
SN - 0098-7484
VL - 194
SP - 899
EP - 901
JO - JAMA: The Journal of the American Medical Association
JF - JAMA: The Journal of the American Medical Association
IS - 8
ER -